摘要
目的 :观察黄芪对早期糖尿病肾病尿白蛋白的含量变化。方法 :选择早期糖尿病肾病治疗组 86例 ,对照组70例 ,用药 4周 ,然后观察 2 4小时尿白蛋白指标变化。结果 :用黄芪治疗后可使尿白蛋白明显下降 ,与对照组比较有显著性差异 (P <0 .0 1)。结论 :黄芪可部分纠正糖尿病早期的肾脏高灌注、高滤过 ,该作用可能与抑制肾脏一氧化氮 (NO)合成有关 ,从而明显降低糖尿病肾病早期患者尿白蛋白的排泄 ,证实黄芪治疗早期糖尿病肾病有效。
Objective:To observe the change of astragalus membranaceus on urinary albumin amount in early diabetic nephrosis.Methods:86 patients of early diabelic nephrosis and 70 controls were selected.After therapy four weeks,the amount of 24 hours urinary albumin was detected.Results:After therapy of astragalus membranaceus,the urinary ablumin was greatly reduced.Compared the controls,the reduction was significance( P <0.01).Conclusion:Astragalus membranaceus can improve the high infusion and filtration of renes in early diabetes mellitus.It could inhibit the compound of urinary albumin of Nitric oxide(NO)in renes and greatly reduced the excretion of urinary ablumin in early diabetic nephrosis.It proved astragalus membranaceus was effective and practical in therapy of early diabetic nephrosis.
出处
《镇江医学院学报》
2001年第2期168-169,共2页
Journal of Zhenjiang Medical College
