摘要
目的 探讨不同分娩方式对产妇及其新生儿促甲状腺激素 (TSH)水平的影响。方法 应用放射免疫分析法 ,检测 2 13例产妇及其新生儿的TSH水平 ,按分娩方式不同分为正常分娩组 140例 ,剖宫产组 38例 ,产钳组 35例。结果 (1)产钳组产妇TSH为 (4 13± 0 6 9)mU/L ,正常分娩组产妇为 (2 5 8± 0 87)mU/L ,两组比较 ,差异有极显著性 (P <0 0 1)。剖宫产组产妇TSH为 (2 81± 0 45 )mU/L ,同产钳组产妇比较 ,差异有极显著性 (P <0 0 1) ;同正常分娩组产妇比较 ,差异无显著性 (P>0 0 5 )。(2 )产钳组新生儿TSH为 (8 85± 2 48)mU/L ,正常分娩组新生儿为 (5 36± 2 2 3)mU/L ,两组比较 ,差异有极显著性 (P <0 0 1)。剖宫产组新生儿TSH为 (3 84± 2 16 )mU/L ,同正常分娩组比较 ,差异有显著性 (P <0 0 5 )。 (3) 3组产妇及其新生儿TSH水平之间呈显著正相关。结论 产妇和新生儿TSH水平的高低与不同分娩方式有关。
Objective To investigate the effect on thyrotropin (TSH) levels of pregnant women and their newborns in different delivery ways. Methods The serum TSH levels of 213 pregnant women and the umbilical cord blood TSH levels of their newborns (140 cases from normal vaginal delivery, 38 cases from cesarean section, 35 cases from low forceps delivery) were tested by immunoradiometric assay. Urinary iodine was detected from pregnant women before delivery. Results In pregnant women, the mean serum level of TSH in the forceps group [(4 13±0 69) mU/L] was significantly higher than those of the normal birth group [(2 58±0 87) mU/L, P <0 01] and the cesarean section group [(2 81±0 45) mU/L, P <0 01]. There was no difference in TSH level between the normal birth group and the cesarean section group. In newborns, the mean TSH level in the forceps group [(8 85±2 48) mU/L] was significantly higher than those of the normal birth group [(5 36±2 23) mU/L, P <0 01] and the cesarean section group [(3 84±2 16) mU/L, P <0 01]. The mean TSH level in the normal birth group was significantly higher than that of the cesarean section group ( P <0 05). The serum TSH levels of pregnant women were positively correlated with the umbilical cord blood TSH levels of their newborns in three groups. Conclusions The contraction of uterus is the stimulus for the surge in TSH levels of pregnant women and their newborns after delivery. It′s reliable that the TSH levels of newborns could be evaluated by monitoring the TSH levels of pregnant woman.
出处
《中华妇产科杂志》
CAS
CSCD
北大核心
2001年第5期282-284,共3页
Chinese Journal of Obstetrics and Gynecology
