摘要
叙述了人类基因组计划 (HGP)实施过程中计算机科学向基因组学领域的不断渗透及面临的挑战。基因组数据库及网络系统的构建与完善为基因组信息的交流提供了基础 ,一系列计算机软件的开发和改进简化了HGP这一繁重的劳动。在HGP的推动下 ,世界各大信息技术公司也加盟到基因组研究中 ,使生物学中融入了更多的计算机专业技能 ,有利于引进新的思维模式 ,开拓新的研究方法。但目前在基因组信息的交流与分析方面 ,标准化和精确性仍显不足 ,信息的处理能力也受到计算机存储量和运算速度的制约 。
This article provides an overview of the application and development of computer science in the progress of Human Genome Project (HGP).The creation and reconstruction of genomic databases and sophisticated network-based informatics are fundamental to the success of this research.A group of computer-based methods and tools are designed and improved,which facilitate the arduous tasks of analyzing genomic data generated in HGP.Because of the driving force of HGP,the world's largest information technology company joined the efforts in genetic research and brought more computer technology to genomics,which would help create new approaches in life science.Currently,the scientific community urgently needs standard and accurate analysis methods for annotation and exchanging of genomic data.A huge increase in computer power is also needed in the management of large-scale data.These problems will be gradually solved with the development of computer science.
出处
《医学与哲学》
2001年第5期14-18,共5页
Medicine and Philosophy
关键词
人类基因组计划
计算机科学
信息学
human genome project (HGP)
computer science
informatics
