摘要
为探讨Ｔｇ在ＩＤＤ研究中的价值，利用两种Ｔｇ药盒（下称Ｔｇ〈Ａ法〉和Ｔｇ〈Ｂ法〉）对相同对象同时测定进行比较。观察对象为长期供碘盐的大别山区霍山县太平畈乡小学和未补碘地区合肥市小学８～１０岁儿童。结果表明大别山组儿童尿碘、血清ＦＴ３、ＦＴ４值均显著高于合肥市组儿童（０．０００５＜Ｐ＜０．０５），Ｔｇ〈Ａ法〉结果与ＴＳＨ值显著低于合肥市组（０．００１＜Ｐ＜０．０５），但Ｔｇ〈Ｂ法〉结果与ＴＳＨ及Ｔ〈Ａ法〉结果相反。两法测定结果无相关性（Ｐ＞０．０５）。Ｔｇ〈Ａ法〉结果与尿碘水平ＴＳＨ值均有显著直线相关关系（Ｐ＜０．００１），而Ｔｇ〈Ｂ法〉结果无上述规律。结论是Ｔｇ在评价碘营养状态时比ＴＳＨ更敏感，药盒的选择是保证结果一致性的关键。
To explore the values of Tg in studying IDD,Tg levels of 8￣10 years old children from Dabie mountainous district and Hefei city,Anhui province were compared by using two kinds of Tg RIAkits (Tg〈A kit〉 and Tg〈B kit〉).The rerults showed levels of urinary iodine and serum FT3、FT4 of children from dabie district wre significantly higher than those of children in Hefei.Tg〈A kit〉 and TSH levels were lower.The Tg〈B kit〉 levels were contrary to the levels of TSH and Tg〈A kit〉.Tg〈A kit〉 levels were significantly correlative with the levels of urinary iodine and TSH.The above results suggested that Tg level is more sensitive for evaluating iodinenutritional status than that of TSH.The selection of Tg RIAkit is very important.
出处
《中国地方病学杂志》
CAS
CSCD
1998年第2期93-95,共3页
Chinese Jouranl of Endemiology
