摘要
本文介绍2-乙酰基-7-甲胺基(艹卓)酮合成方法的改进——用挥发性小的低浓度甲胺溶液与3-乙酰基(艹卓)酚酮反应;和采用直接减压蒸除溶剂法分离产品,得到较好产率的2-乙酰基-7-甲胺基(艹卓)酮(I);用化合物(I)与三溴化苯基三甲铵(PTT)反应,得到两种至今未见文献报道的新化合物.其结构经红外光谱、核磁共振谱及元素分析证明为2-乙酰基-溴代-7-甲胺基(艹卓)酮(II)和2-(2,2一二溴乙酰基)-溴代-7-甲胺基(艹卓)酮(Ⅱ)..
In this paper, the improvement of synthetic method of 2-acetylaminotropone is introduced. 3-Acetyltropolone reacted with low concen-tration methylamine solution and solvent was directly evaporated in reduce pres-sure to give 2-acetyl-7 -methylaminotropone(I) in good yield. The compound (I) reacted with phenyltrimethylammonium tribromide (PTT) to give two new compounds. The structures of these products were proved by IR, 1HNMR and ele-mental analysis. They are 2-acetyl-bromo-7-methylaminotropone
(Ⅱ) and 2-( 2,2-dibromoacetyl) - bromo-7-methylamino-tropone (Ⅲ).
出处
《黑龙江大学自然科学学报》
CAS
1991年第4期94-97,共4页
Journal of Natural Science of Heilongjiang University
关键词
Zhou酮
合成
PTT
反应
Key Wrods: tropone, synthetic method, reaction
