摘要
应用^(125)I—UdR释放法对25例正常人及50例慢性肝病患者外周血NK活性进行了观察.发现男性NK活性(平均为59.8±10.5%)显著高于女性者(平均为41.0±6.5%)P<0.05.慢性肝病患者NK活性(平均为31.8±18.8%)显著低于正常对照者(平均为57.4±11.0%)P<0.001.且肝硬化病人NK活性(平均为31.6±16.5%)显著低于慢性肝炎者(平均为35.8±18.5%)P<0.05。推测慢性肝病患者NK活性降低可能与乙肝病毒感染有关系。
The activity of the natural killer cells(NK)in the peripheral blood of 25 normal persons and 50patients with chronic liver diseases was studied with ^(125)I--UdR release method. The results showed thatthe NK activity in the male (mean 59. 8±10. 5%) was significantly higher than that in the female(mean 41. 0±6. 5%) P<0. 05. The NK activity in the patients with chronic liver diseases (mean31. 8±18. 8%) was significantly lower than that in the normal persons (mean 57. 4±11. 0%)P<0. 001,and the NK activity in the patients with liver cirrhosis (mean 31. 6±16. 5%) was significant-ly lower than that in the patients with chronic hepatitis (mean 35. 8±18. 5%) P<0. 05. It is be-lieved that the reduction of the NK activity in the patients with chronic liver diseases is related to Bhepatitic virus.
出处
《河南医科大学学报》
1991年第3期229-231,共3页
Journal of Henan Medical University
关键词
乙型肝炎
自然杀伤细胞
活性
liver cirrhosis
chronic hepatitis
B hepatitic virus
natural killer cell activity
