2Cush JJ, L ipsky PE, Postlethwaite AE, et al. Correlation of serologic indicators of inflammation with effectiveness of nonsteroidal antiinflammatory diug therapy in rheumatoid arthritis. Arthritis Rheum, 1990, 33:19
3Kirwan JR. The effect of glucocorticoids on joint destruction in rheumatoid arthritis. N Eng J Med, 1995,333:142
5Weinblatt ME, Weissman BN, Holdsworth DE, et al. Long - term prospective study of methotrexate in the treatment of rheumatiod arthritis,84 - month update. Arthr Rheum, 1992,35:129
2Smolen JS,Kalden JR,Scott DI,et al.Efficacy and safety of leflunomide compared with placebo and sulphsalazine in active rheumatoid arthritis: a doubleblind, randomised, multicentre trial[].The Lancet.1999
3Fox RI.Mechanism of action of leflunomide in rheumatoid arthritis[].Journal of Rheumatology The.1998
4Ruckermann K,Fairbanks LD,Carrey LA,et al.Leflunomide inhibits pyrimidine denovo synthesis in mitogen-stimulated T lymphocytes from healthy humans[].Journal of Biological Chemistry.1998