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以表皮生长因子受体为靶向的肿瘤信号转导干预治疗 被引量:6

EGFR as a target for signal transduction interference therapy in human cancers
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摘要 表皮生长因子受体 (EGFR)在相当一部分的人类肿瘤细胞存在高表达 ,且其所介导的信号转导与肿瘤的发生发展及预后密切相关 ,以其为靶子进行的肿瘤信号转导干预治疗是一种较佳的策略之一 ,为肿瘤治疗提供了可喜的前景。
出处 《国外医学(肿瘤学分册)》 2001年第2期120-123,共4页 Foreign Medical Sciences (Cancer Section)
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  • 1Wong L,Deb TB,Thompson SA,et al.A differential requirement for the COOH-terminal region of the epidermal growth factor(EGF)receptor in amphiregulin and EGF mitogenic signaling[].Journal of Biological Chemistry.1999
  • 2Sun Y,Fry DW,Vincent P,et al.Growth inhibition of nasopharyngeal carcinoma cells by EGF receptor tyrosine kinase inhibitors[].Anticancer Research.1999
  • 3Johnson AC,Murphy BA,Matelis CM,et al.Activation protein-1 mediates induced but not basal epidermal growth factor receptor gene expression[].Molecular Medicine.2000
  • 4Huang SM,Harari PM.Modulation of radiation response after epidermal growth factor receptor blockade in squamous cell carcinomas: inhibition of damage repair, cell cycle kinetics, and tumor angiogenesis[].J Clin Cancer Res.2000
  • 5Xiao ZQ,Majumdar AP.Induction of transcriptional activity of AP-1 and NF-kappaB in the gastric mucose during aging[].American Journal of Physiology Gastrointestinal and Liver Physiology.2000
  • 6Gutacker C,Klock G,Diel P,et al.Nerve growth factor and epidermal growth factor stimulate clusterin gene expression in PC12 cells[].Biochemical Journal.1999
  • 7Beers R,Chowdhury P,Bigner D,et al.Immnotoxins with increased activity against epidermal growth factor receptor vⅢ-expressing cells produced by antibody phage display[].Clinical Cancer Research.2000
  • 8Sampson JH,Crotty LE,Lee S,et al.Unarmed, tumor specific moncolomal antibody effectively treats brain tumors[].Proceedings of the National Academy of Sciences of the United States of America.2000
  • 9Shi W,Fan H,Shum L,et al.The tetraspanin CD9 associated with transmembrane TGF-alpha and regulates TGF-alpha induced EGF receptor activiation and cell proliferation[].The Journal of Cell Biology.2000
  • 10Hirao T,Sawada H,Koyama F,et al.Antisense epidermal growth factor receptor delivered by adenoviral vector blocks tumor growth in human gastric cancer[].Cancer Gene Therapy.1999

同被引文献64

  • 1杨竹林,李永国,庄赞根,吕芳.胆系恶性肿瘤表皮生长因子受体的表达及其生物学意义[J].中华实验外科杂志,1994,11(2):106-107. 被引量:3
  • 2陆澄,曾水林,张郢华,杨鹏.胰腺癌组织中P21(WAF1)、转化生长因子α、表皮生长因子受体表达与神经浸润转移的关系[J].南通大学学报(医学版),2006,26(1):31-32. 被引量:6
  • 3昌红,王振华,严庆汉,李鸿江,柴敏秀.表皮生长因子受体在早期胃癌中的表达[J].诊断病理学杂志,1996,3(1):18-19. 被引量:11
  • 4Naoko I.Expression of GDNF correlates with perineural invasion of bile duct carcinoma[J].Cancer,2002,94:167-174.
  • 5Nagakawa T,kauahara M,Ueno k,et al.A clinicopathologic study on neural invasion in cancer of the pancreatic head[J].Cancer,1992,15,(69):930.
  • 6Biswas DK,Cruz AP,Gansberger E,et al.Epidermal growth factor induced nuclear factor activation:a major pathway of cell cycle prograss in estrogen receptor negative breast cancer cell[J].Proc Natl Acad Sci USA,2000,97(15):8542-8547.
  • 7Bockman DE,Buchler M,Beger HG.Interaction of pancreatic ductal carcinoma with nerve damage[J].Gastroenterology,1994,107:219.
  • 8Dupont A, Corseaux D, Dekeyzer O, et al. The proteome and secretome of human arterial smooth muscle cells. Proteomics, 2005,5(2): 585-596
  • 9Dupont A, Tokarski C, Dekeyzer O, et al. Two-dimensional maps and databases of the human macrophage proteome and secretome.Proteomics, 2004, 4 (6): 1761- 1778
  • 10Martin D B, Gifford D R, Wright M E, et al. Quantitative proteomic analysis of proteins released by neoplastic prostate epithelium.Cancer Res, 2004, 64 (1): 347-355

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