摘要
目的 :观察竹黄颗粒剂Ⅱ号对肝气郁结型银屑病的临床疗效。方法 :将 67例患者随机分为竹黄颗粒剂Ⅱ号治疗组 (简称实验组 ,34例 )和复方青黛胶囊对照组 (简称对照组 ,33例 ) ,观察治疗后的临床疗效 ,并进行主要症状、皮损评估。对 15例银屑病患者与 13名健康人血浆中P物质 (SP)、血管活性肠肽(VIP)的含量进行放射免疫测定。结果 :两组总有效率分别为 97 1%、78 8% ,经统计学处理 ,差异有显著性(P <0 0 5) ;竹黄颗粒剂Ⅱ号能降低肝气郁结型银屑病患者的SP、VIP的含量 (P <0 0 1)。结论 :竹黄颗粒剂Ⅱ号治疗肝气郁结型银屑病疗效满意 ,值得进一步研究。
Objective: To observe the efficacy of Zhuhuang Granule No.2 (ZHG2) in treating psoriasis with Liver Qi stagnancy. Methods: Sixty seven patients were randomly divided into two groups, the 33 patients in the control group were treated with composite indigo capsule and the 34 in the treated group treated with ZHG2, and the clinical effect, changes of main symptoms and local skin lesion after treatment were evaluated. Meanwhile, the plasma levels of substance P (SP) and vasoactive intestinal peptide (VIP) in 15 patients and 13 healthy subjects were measured using radioimmunoassay (RIA). Results: The total effective rate in the treated group and the control group was 97.1% and 78.8% respectively with significant difference, P<0 05. ZHG2 showed a significant effect in reducing plasma level of SP and VIP in patients of psoriasis with Liver Qi stagnancy. Conclusion: The effect of ZHG2 in treating psoriasis patients with Liver Qi stagnancy is satisfactory, and worth further studying.
出处
《中国中西医结合杂志》
CAS
CSCD
北大核心
2001年第4期269-271,共3页
Chinese Journal of Integrated Traditional and Western Medicine
基金
湖南省卫生厅资助!课题 (No .2 0 0 0 0 37)
