摘要
目的 寻求高炉锰铁冶炼致职业暴露人群锰中毒的防治对策。方法 用职业流行病学的方法对某公司高炉锰铁冶炼的职业卫生监督监测和职业暴露人群追踪 35年的资料进行分析研究。结果 车间空气中锰浓度最高 199.4mg/m3 ,最低 0 .0 34mg/m3 ,平均 2 .0 46mg/m3 。随着技术改造的不断深入 ,车间空气中锰浓度呈显著下降趋势。累计追踪观察 15 5 5例锰暴露人群 ,共诊断锰中毒 39例 ,患病率 2 .5 0 8%。发病工龄最短 3年 ,最长 34年 ,平均 14年。采取依地酸二钠钙 (CaNa2 EDTA)、二巯基丁二酸 (DMSA)、对氨基水杨酸 (PAS)等驱锰 ,辅以能量合剂、维生素和普鲁卡因封闭 ,中药扶正、助阳、补气及调离锰暴露岗位等综合措施 ,疗效肯定 ;脑血流图 (REG)、脑多普勒 (TCD)、神经行为功能等检验指标 ,对锰中毒的诊断有一定参考价值。结论 改善生产环境 ,加强健康监护 ,积极治疗中毒患者 ,将有助于预防锰中毒的发生 。
Objective To seek the measures for prophylaxis and treatment of occupational manganism among high furnace ferromanganese smelting workers. Methods Data of 35 year occupational health supervision,and clinical therapy and prevention of manganism among workers exposed to manganese were analyzed with the method of occupational epidemiology. Results In the workplace,the maximum manganese content in the air was 199.4 mg/m 3,minimum 0.034 mg/m 3 and average 2.046 mg/m 3.As the techology continuously improved,the manganese content in the air was gradually decreasing.Of 1?555 followed up Mn exposed workers,the incidence was 2.508%.The shortest diseased work year was 3 a,the longest 34 a,average 14 a.Using disodium coolium ethylene diamine tetraacetate(CaNa 2EDTA),2,3 dimercaptosuccinic acid(DMSA), p aminosalicylic acid(PAS) etc to scavenge Mn,supplemented with ATP mixture,vitamin,procaine block,traditional Chinese medicine and moving the patients away from the manganese exposed spot etc were effective therapy.Rheoencephalography(REG),transcranial doppler(TCD) and neurobehavioral function were of certain reference value for diagnosis. Conclusion Improving the workplace environment,strengthenning health monitor and actively treating manganism patients,will help prevent the occurrence of manganism and recover from manganism.
出处
《中华劳动卫生职业病杂志》
CAS
CSCD
北大核心
2001年第2期118-120,共3页
Chinese Journal of Industrial Hygiene and Occupational Diseases
关键词
锰中毒
防治
研究
锰铁冶炼
Manganism
Study of prophylaxis and treatment
Ferromanganese smelting