摘要
目的探讨载脂蛋白 (Apo)和脂蛋白 (a)〔L p(a)〕与 2型 DM合并脑梗塞的关系。方法运用配比的病例对照研究方法 ,使用 L ogistic回归模型进行分析。结果以其他病人作为对照 ,Apo和 L p(a)与 2型 DM合并脑梗塞有关 ;2型 DM病人作为对照仅发现 L p(a)与 2型 DM合并脑梗塞有关。经以 2型 DM为对照人群归因危险比(PARP)分析 ,L p(a)的 PARP高达 75 .6 7%。结论 L p(a)是 2型 DM合并脑梗塞的独立危险因素。为了降低 2型DM合并脑梗塞的危险性 ,应注意控制 L p(a)
Objective The cerebral infarction, a common acute cerevascular disease, is one of the main complication of type 2 diabetes mellitus (T2DM). We studied on the relationship of Apo, Lp(a) and cerebral infarction in T2DM patients. Methods A pair matched case control study was carried out. Data was analyzed by Logistic regression. Results Apo and Lp(a) were related to cerebral infarction in T2DM compared with other kind of patients. While compared with T2DM patients, only Lp(a) was related to T2DM complication cerebral infarction. The results showed that the PARP of Lp(a) was 75 67%. Conclusion Lp(a) was an independent risk factors for T2DM patients complicated with cerebral infarction. Controlling the level of serum Lp(a) would decrease the risk of cerebral infarction in T2DM patients.
出处
《中国慢性病预防与控制》
CAS
2001年第2期67-69,共3页
Chinese Journal of Prevention and Control of Chronic Diseases
