摘要
目的 研究视网膜色素变性 (retinitis pigmentosa,RP)的脉络膜血液循环特征。 方法 对37例 RP患者行吲哚青绿血管造影 (indocyanine green angiography,ICGA) ,并与正常人眼对照。 结果 1RP组眼底荧光最早出现的平均时间 (14.38± 3.95 ) s,脉络膜静脉荧光开始充盈的平均时间 (17.2 7±5 .94) s,与对照组比较差异无显著性的意义 (P >0 .0 5 )。 2 RP组脉络膜血管荧光减弱的平均时间(4 75 .75± 15 3.70 ) s,较对照组明显缩短 (P<0 .0 0 0 1)。 3RP组眼底后部强荧光区的平均面积 (4 1.2 0±19.99) mm2 ,较对照组明显缩小 (P<0 .0 0 0 1)。 4ICGA中后期 RP组纱幕状荧光缺如 6 1只眼 ,占 84.7% ;斑状强荧光 2 1只眼占 2 9.2 % ,4只眼强荧光点渗漏 ,占 5 .6 %。 结论 1RP脉络膜血管灌注压无改变 ;2RP脉络膜血流量减少 ;3RP脉络膜毛细血管萎缩 ;
Objective To study the characteristics of choroidal circulation in RP. Methods Using ICGA to observe 37 cases of RP and compare with healthy volunteers. Results ① The earliest fluores-cein filling time of the choroidal arteries in RP group was (14.38±3.95) seconds,the choroidal veinous in RP group was (17.27±5.94) seconds,and there was no obvious difference between RP and control group.②The fluorescein failing time of choroidal vein in RP group was (475.75±153.70)seconds.③The area of the bright fluorenscence in posterior fundus in RP group was (41.20±19.99) mm2,and compared with the control group,there was significant difference (P<0.0001).④In the mid to late phase during ICGA,in RP group the veil-like hypofluorescence was found in 61 eyes (84.7%),plaque hyperfluorescence in posterior fundus in 21 eyes (29.2%),and leakage of heperfluorescence in 4 eyes(5.6%). Conclusion [WT5”BZ]①The perfusionpressure of choroidal vessels in RP reveals no change.②The blood volume of choroidal vessels becomesdecreased in RP.③The choroidal capillaries become atrophic in RP.④Choroidal neovascularization may occur in patients with RP.
出处
《中华眼底病杂志》
CAS
CSCD
2001年第1期26-29,共4页
Chinese Journal of Ocular Fundus Diseases
基金
河南省科委资助攻关课题! (941 2 0 0 4 4 7)
