摘要
目的 :评价清眩降压片治疗高血压病的临床疗效。方法 :选择高血压病患者 16 0例 ,随机分为 4组 ,分别服用清眩降压片 (0 .6 g~ 1.5 g ,3/d) ,硝苯地平控释片 (5mg~ 10mg ,2 /d)、卡托普利 (12 .5mg ,2 5mg ,3/d)及阿替洛尔 (6 .2 5mg~2 5mg ,3/d) ,连续 30d ,每 5d 1次观察临床疗效、降压幅度和心率变化。 结果 :清眩降压片组降压有效率为 82 .5 % ,低于硝苯地平控释片组 (94.6 % )和卡托普利组 (91.5 % ) ,高于阿替洛尔组 (75 .0 % )。清眩降压片组降压达到正常范围的时间迟于硝苯地平控释片和卡托普利组 ,早于阿替洛尔组 ,无明显副作用。结论 :清眩降压片治疗高血压疗效确切 ,较硝苯地平控释片、卡托普利及阿替洛尔适用范围广。
Objective: To evaluate the curative effect of Qingxuanjianyia Tablets on hypertension. Methods: 160 cases with hypertension were randomizedly divided into 4 groups: Qingxuanjianyia Tablets(in a dose of 0.6~1.5g, 3 times a day), nifedipine(in a dose of 5~10mg, 2 times a day), captopril(in a dose of 12.5mg, 2~3 times a day) and atenolol(in a dose of 6.25~25mg, 3 times a day) on 30 successive days. The curative effect, hypertension lowering range and change of heart rate were observed every 10 days. Results: The total effective rate of Qingxuanjianyia Tablets group was 82.5% and lower than that of nifedipine group (94.6%) and captoril group(91.5%), but higher than that of atenolol group(75.0%). The time of reaching normal blood pressure of Qingxuanjianyia Tablets group was later than that of nifedipine and captoril groups, but more early than that of atenolol group. Qingxuanjianyia Tablets has no side effects. Conclusion: Qingxunjianyia Tablets is effective for hypertension and has a wider application than nifedipine, captoril and atenolol.
出处
《中成药》
CAS
CSCD
北大核心
2001年第3期193-195,共3页
Chinese Traditional Patent Medicine