摘要
目的 :调查鄂西北地区 90年代钩端螺旋体 (简称钩体 )病流行情况。方法 :病人血清检测采用MAT和Dot -ELISA法 ,健康人群免疫水平检测采用MAT法 ,传染源调查用夹夜法捕鼠 ,培养鼠肾和猪肾皮质 ,分离钩体并鉴定钩体菌群。结果 :90年代前鄂西北地区很少发生钩体病 ,90年代后 ,该地区竹溪、竹山、襄阳、宜城等县市发生钩体病 96 4例 ,占该地区 40年总发病数的 88.93%。钩体病暴发时间主要集中在 9～ 10月 ,钩体病人临床类型以流感伤寒型和肺出血型为主 ,分别占调查总数的 70 .47%和 2 1.12 %。鼠密度 3.6 2 % ,鼠带菌率 14.37% ,健康人群血清抗体阳性率 41.5 0 %。结论 :钩体病人感染菌群以黄疸出血群为主 ,与当地鼠。
Objective:Investigate the epidemic of leptospirosis in north-west of Hubei province in 1990'S.Methods:The serum of leptospirosis cases were measured using MAT and Dot-ELISA methods,health population immune level with MAT method. The investigation of the source adopt mouse-clip in the evening, cultivatet rat and pig kidney cortex, separate leptospiroal and identify leptospiroal serum groups.Results:The cases of leptospirosis were few 1990s ago and later the continued outbreaks of leptospirosis were in Zhuxi,Xiangyang and Yicheng and so on in north-west of the Hubei province. All patients (964) accounted for 88.93 % in cases of 40 years. The time of outbreak mostly centred on September to October,which prolonged for about one month than that in brief precent areas of all Hubei province. The patient's clinical categories were grippotyphosa type and lung bleed type,which accounted for 70.47 % and 21.12 % respectively in all patients. The density of mice was 3.62 % and mice carrier rate 14.37 %. The positive rate of antibody was 41.50 % in healthy groups. Conclusions:The leptospiral groups among leptospiral patients were mainly icterohaemorrhagiae. They carried the same groups of source of infection such as pigs and mice.
出处
《中国媒介生物学及控制杂志》
CAS
CSCD
2001年第2期118-119,共2页
Chinese Journal of Vector Biology and Control
