摘要
目的：探讨与膀胱癌相关的尿道癌的发病特点及诊治。方法：对４７１例膀胱移行细胞癌中发生的１６例尿道受累的发病特点进行分析，结合文献讨论本病的诊断及治疗方法。结果：尿道移行细胞癌发生率占同期膀胱癌患者的３．４％；１６ 例膀胱瘤累及尿道的患者皆为男性；膀胱癌多发（包括原位癌）的１３例；肿瘤侵犯膀胱颈部或三角区的１４例；膀胱癌病理分级Ⅱ级：７例，Ⅲ级：９例。结论：膀胱多发肿瘤、位于膀胱颈或三角区的肿瘤以及高分级肿瘤是尿道癌发生的危险因素。尿道肿瘤的诊断依靠膀胱尿道镜检查及活检、尿道冲洗液脱落细胞学检查，膀胱切除术中标本尿道切缘冰冻病理检查时诊断和确定治疗方案有重要意义。
Objective To study the characteristics of urethral tumor involvement in the male patients with transitional cell carcinoma (TCC) of bladder and its diagnosis and treatment. Methods: The clinical data of 16 patients with urethral involvement out of 471 patients with bladder cancer were reviewed. Results: The occurrence rate of urethral involvement was 3.4%. All the 16 patients were male. In 13 patients, the primacy lesion of the bladder were either multifocal or carcinoma in situ. In 14 patients, the primary lesions in the bladder were located either in the bladder neck or in the trigone. Histopathologics of the bladder cancer with urethral involvement were 7 patients of Grade Ⅱ and 9 patients of Grade Ⅲ. Conclusion: Significant risk factors for the occurrence of urethral involvement in patients with bladder cancer are multifocal tumors, carcinoma in situ, tumors in the bladder neck or trigone and high histological Grade of TCC. The urethral lesions can be detected by cysto-urethroscopy and biopsy, urethral washing cytology as well as pathologic analysis of the specimens of cystectomy. Frozen urethral margin section during cystectomy may be helpful in decision of prophylactic urethrectomy.
出处
《中国肿瘤临床》
CAS
CSCD
北大核心
2001年第3期211-213,共3页
Chinese Journal of Clinical Oncology
关键词
尿道上皮肿瘤
移行细胞癌
膀胱癌
男性
Urothelial Carcinoma Transitional cell carcinoma Cancer of bladder Urethral cancer
