摘要
目的 了解精神分裂症患者淋巴细胞核原癌基因 (FOS)蛋白表达与细胞免疫的关系。方法 检测精神分裂症 (SCH)外周血CD亚型淋巴细胞转化实验 (LTT) ,及正常人淋巴细胞在SCH血清作用下核FOS蛋白表达情况。结果 初发组淋巴细胞转化率明显降低 ,核FOS蛋白表达异常。结论 核FOS蛋白的异常表达可能与细胞免疫异常有关。
Objective To discuss the relation of c FOS proteion expression in lymphocyte to its cellular immune. Methods To analyze the schizophrenic lymphocyte membrane markers CD + 3,CD + 4,CD + 8 and lymphocyte transforming test, and also examine c fos protein expression in PBC under SCH serum. Results The result was that LTT and c FOS protein were significantly decreased in drug free, first episode SCH. Conclusions The c FOS superexpression may be related to lymphocyte immune depression of SCH.
出处
《中国神经精神疾病杂志》
CAS
CSCD
北大核心
2001年第2期93-94,共2页
Chinese Journal of Nervous and Mental Diseases
基金
国家自然科学基金资助项目! (编号 :396 70 2 73)
