摘要
本文观察了112例原发性高血压患者以及70例正常人的血清IgG、IgM和C_4水平。结果高血压组IgG值高于对照组，但无统计学意义。若以正常对照组IgG值均数加一个标准差为正常高限，则高血压组中IgG值超过正常者占28.6％，明显高于对照组14.1％（p＜0.05）。且IgG升高的百分率随高血压病期的加重而增加。3例IgG升高的高血压患者用小剂量环磷酰胺治疗一个月，IgG值均下降至正常范围，其中2例治疗后血压明显下降。研究结果提示，原发性高血压患者有IgG升高的趋势，IgG升高与高血压患者的血管损伤有关。
Serum IgG,, IgM,and C4 were measured in 112 patients with essential hyper-
tension(EHT) and 70 normal controls. It was found that IgG, IgM and C4 levels
in EHT patients were, as those in controls. However, the incidence of elevated
IgG in patients (28.6%) was much higher than it was in controls (14.1%)
(P<0.05). In two treated patients the blood pressure lowered markedly,and it sho-
wed simultaneous recovery of humoral immunity. The results suggest that the im-
munological mechanisms are likely connected with vascular damage in EHT. The num-
ber of patients treated with cyclophosphamide was too small to draw a conclusion.
出处
《重庆医药》
CSCD
1990年第1期1-3,共3页
