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抗高血压药 非洛地平(Felodipine) 被引量:4

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摘要 化学名 3,5-吡啶二羧酸,4-(2,3-二氯苯基)-1,4-二氢-2,6-二甲基,乙基甲基酯药效分类钙拮抗剂开发单位 (瑞典)Astra 上市厂商 (瑞典)Astra 1988年上市有机钙拮抗剂是一类具有舒张血管作用的物质,但一些老的钙拮抗剂在治疗量时对心脏尚具有负性的肌力作用。
作者 程玲云
出处 《国外医药(合成药.生化药.制剂分册)》 1991年第1期46-47,共2页 World Pharmacy
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同被引文献21

  • 1梁竹,王宝德,于燕莉,谢继青,芦怀平,袁成.不同产品非洛地平缓释片药物动力学比较[J].中国临床药理学与治疗学,2005,10(5):551-554. 被引量:11
  • 2LI Yan-yan,YIN Yi-zi,SUN Zhi-hui,LI Xin,HU Li-gang,LI Peng-fei,ZHONG Da-fang.Sensitive and Rapid Quantification of Felodipine by High-performance Liquid Chromatography-tandem Mass Spectrometry(HPLC-MS/MS) and Its Pharmacokinetics in Healthy Chinese Volunteers[J].Chemical Research in Chinese Universities,2006,22(4):479-483. 被引量:5
  • 3钟大放.以加权最小二乘法建立生物分析标准曲线的若干问题[J].药物分析杂志,1996,16(5):343-346. 被引量:583
  • 4Dru JD, Hsieh JY, Matuszewski BK, et al. Determination of felodipine, its enantiomers, and a pyridine metabolite in human plasma by capillary gas chromatography with mass spectrometric detection[ J]. J Chromatogr B Biomed Appl, 1995, 666(2):259.
  • 5Lindmark B, Ahnoff M, Persson BA. Enantioselective determination of felodipine in human plasma by chiral normal-phase liquid chromatography and electrospray ionisation mass spectrometry[J]. J Pharm Biomed Anal,2002,27(34) :489.
  • 6Lundahl J,Regardh CG,Edgar al.Effects of grapefruitjuice ingestion-pharmacokinetics and haemodynamics of intra-venously and orally administrated felodipine in healthy men[J].Eur J Clin Pharmacol,1997,52:139-145.
  • 7Lown KS,Bailey DG,Fontana RJ,et al.Grapefruit juice in-creases felodipine orall availability in humans by decresing in-testinal CYP3A protein expression[J],J Clin Invest,1997,99(10):2545-2553.
  • 8Paine MF,Widmer WW,Hart HL,etal.A furanocoumarin-free grapefruit juice establishes furanocoumarins as the media-tors of grapefruit juice-felodipine interaction[J],Am J ClinNutr,2006’ 83:1097-1105.
  • 9Florin A,luliana S,Florentin T,et al.On-line SPE on re-stricted access adsorbent for HPLC-MS/MS analysis of felo-dipine in plasma samples[J].Analytical Letters,2010,43:130-1343.
  • 10Dru JD,Hsieh JY,Matuszewski BK,et al.Determination offelodipine,its enantiomers,and a pyridine metabolite in hu-man plasma by capillary gas chromatography with mass spec-trometric detection[J],J Chromatogr B,1995,666(2):259-267.

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