摘要
目的检测缺铁大鼠耳蜗组织微量元素含量及听阈改变。方法复制缺铁大鼠模型，测大鼠客观听阈改变，用原子吸收光谱法测定大鼠血清微量元素及耳蜗组织微量元素含量。结果缺铁组和正常组大鼠血清铁分别为 (14.93± 9.72)μ mol/L、 (46.11± 18.3)μ mol/L；缺铁组和正常组大鼠耳蜗组织铁含量分别为 (179.80± 24.70)pmol/L， (410.18± 111.96)pmol/L；缺铁组大鼠听阈提高 >15 dB的发生率远高于对照组。结论缺铁大鼠不仅血清铁降低，耳蜗组织铁也降低，同时影响到耳蜗听功能。
Objective To determine the iron concentration in cochlear tissue and serum of iron－ deficient rats and changes in auditory thershole. Method The determination of iron concentration in cochlear tissue and serum were assessed by atomic absorptin spectrophotometry after reconstruction of iron－ deficient rats.Results The concentration of iron in serum of iron－ deficient group and normal group are(14.93± 9.72)μ mol/L、 (46.11± 18.3)μ mol/L.The iron concentration in cochlear tissue of iron－ deficient group and normal group are (179.80± 24.70)pmol/l,(410.18± 111.96)pmol/L.Auditory threshold incresed by 15 db or more was more common in iron－ dificient group compared with control group.Conclusion The concentration of iron in cochlear tissue and serum of iron－ deficient rats are blow affecting auditory function of cochlear tissues.
出处
《现代康复》
CSCD
2001年第3期63-63,共1页
Modern Rehabilitation
关键词
耳蜗
微量元素
缺铁
耳聋
cochlea
trace element
iron－ deficiency
hearing loss
