摘要
目的探讨早期干预对新生儿缺氧缺血性脑病 (HIE)预后的影响。方法将 62例中、重度 HIE患儿自恢复期起随机分成干预组 34例和对照组 28例。干预组从新生儿期开始接受早期干预，两组在性别、父母文化、环境条件、家庭经济收入方面相仿，所有病例均于出生 6、 12、 18个月龄时进行精神运动发育随访和检测。结果相同月龄干预组发育商 (DQ)明显高于对照组 P< 0.05、 0.01、 0.01。，康复率高，预后不良发生率低 (P<0.05)。结论对 HIE患儿早期给予持续的干预，能有效地促进其精神运动发育，是改善预后、减少后遗症发生率，提高患病小儿生存质量的有效手段。
Objective To detect the effects of early medical intervention on prognosis of newborn Hypoxic－ ischemic encephalopathy(HIE).Methods 62 severe to moderate HIE newborns were randomly divided into intervention group(34 cases)and control group(28 cases).The intervention group accepted trentment when they are newborn .Sexes,mothers'educational backgrond,enviroment and family income were similar for 2 groups.At the age of 6,12,and 18 months,the assessment and mental development were conducted in two groups. Results The development quotient(DQ)of the intervention group was higher than that of the control group(t=2.3166,2.7298,2.8377， P< 0.05,< 0.01,< 0.01).The intervention group had higher rate of recovery and lower rate of unfavourble prognosis(χ 2=4.1 031,P< 0.05).Conclusion Early continue intervention could promote the mental motor development,improve the prognosis, reduce the rate of the sequela and improve quality of life.
出处
《现代康复》
CSCD
2001年第3期41-42,共2页
Modern Rehabilitation
关键词
新生儿
缺氧缺血性脑病
早期干预
预后
newborn
hypoxic－ ischemic encphalopathy
intervention
prognosis
