摘要
本文报告208例糖尿病(Ⅱ型)常规法尿蛋白阴性者及177例正常健康人所测得的尿白蛋白排出量。结果表明208例患者中的131例(62.98%)尿白蛋白排出量显著高于正常健康人(P<0.001)。尿白蛋白含量随病程和血糖的增加而增高、尿白蛋白排出量与血糖控制程度有关。63例患者经正规抗糖尿病治疗后,尿白蛋白的排出量逐渐降低,治疗3个月后,与正常健康人相比已无显著差异,P>0.05。研究表明,尿白蛋白测定可作为糖尿病肾病早期诊断的指标及早期糖尿病肾病尿白蛋白可以逆转。
The results of urine albumin determination in 208 patients with non-insulin dependentdiabetes mellitus but tested negative for urinary protein on routine examination and in 177normal controls were reported.The results showed that the excretion of urine albumin in131 patients was obviously higher than that in normal controls(p<0.001).In the diabeticpatients tested negative for urinary protein on routine examination,the excretion of urinealbumin was found to be increased in 62.98%,and increased with the duration of diabetesand fasting blood glucose level.After treatment,the excretion of urine albumin decreasedgradually and became normal after 3-month therapy.Moreover,it was found that the excre-tion of urine albumin was correlated with the level of fasting blood glucose.The aforemen-tioned results suggest that the determination of urine albumin could be used as an index ofearly diagnosis of diabetic nephropathy and urine albumin could reversed in early diabeticnephropathy.
出处
《上海医学》
CAS
CSCD
北大核心
1993年第2期74-76,共3页
Shanghai Medical Journal
