摘要
鼾症是由于睡眠时上呼吸道间歇性萎陷引起的呼吸障碍。为了从病理生理角度阐述ＯＳＡＳ和鼾症对人体的危害以及寻找一种评价手术疗效的客观指标，本研究对４３例患者手术治疗前后甲皱（ｎａｉｌｆｏｌａ）微循环的加全积分值进行统计学处理，结果表明有极显著的差异（ｐ＜０．０１），即治疗后微循环积分值的下降有非常显著的意义。其中以流速、红细胞聚集、清晰度以及渗出积分值的降低为著，而形态的改变无显著性差异。这说明，手术治疗鼾症短期内对改善血液流态效果较著，氧代谢对微循环形态的影响则是一个慢性的过程。在对合并高血压患者与不伴高血压患者术后微循环变化的分析研究中发现，前者术后微循环改善程度较后者为著（Ｐ＜０．０１）。表明高血压患者微循环对氧的敏感性更大。另一方面说明鼾症对高血压患者的影响大于对非高血压患者。
Abstract Sever snoring wit h obst ructive sleep apnea is a relat ively common and pot en tially life-threatening disorder characterized by repeated periodic closure of the pharyngeal airway dur-ing sleep.Metabolic,abnormality,cardiobascular system changing and nervous system lesion can be observed in the sever cases. We investigated 43 patients who were admitted to our hospital with the complaint of sever snoring. 26 patients underwent a UPPP that was associ-ated with a tonsillectomy,three patients received nasal surgery,l patient underwent a tonsil-lectomy. Observation of nailfold microcirculation had been studied in all these 30 patients be-fore and five to seven days after the operation. The results showed follows:(1)All of 43 pa-tients had a favorable response to treatmant. Snoring disappeared in 21 patients. The sound of snoring became weak in 20 patients.Sleeping apnea disappeared in 2 pateints although they complained that snoring did not disappear.(2)After treatment,blood flow veloeity,aggregation of erythrocytes and the total integral were significantly different(P<0.001～0.005).Abnormal capillary lcops was not significant different.It was suggested that there was relationship between surgical treatment and improved microcirculation.
出处
《耳鼻咽喉（头颈外科）》
1995年第4期223-226,共4页
Chinese Arch Otolaryngology-Head Neck Surg
