摘要
本文选用了三种二茂铁季铵盐: C_2H_5F′c—CH_2—N(CH_2)_3I、C_5H(17)—F′c—CH_2(CH_3)3 为电极活性材料,邻苯二甲酸二丁酯、邻苯二甲酸二壬酯为增塑剂,制备了药物甘草次酸和布洛芬电极,其中以C_5H_(17)—F′c—CH_2N^+(CH_3)3I^-为活性材料,邻苯二甲酸二丁酯为增塑剂制备的甘草次酸电极和布洛芬电极性能较好,甘草次酸电极的线性响应范围为10(-5)mol/L～10(-2)mol/L,斜率为45mV(13℃),检测下限为6.3×10(-7)mol/L,pH范围为7.6～10.6,用直接电位法测定甘草次酸的回收率为98.5％～101.8％;布洛芬电极的线性响应范围为10(-5)mol/L～10(-2)mol/L,斜率为58mV(15℃),检测下限为8.5×10(-7)mol/L,pH范围为6.8～10.0,布洛芬的回收率为97.5％～99.5％。
In this paper, three ferrocene quaternary ammonium salts are introdued as ion-associate electroactive material for Subglycyrrhelinic Acid and Ibuprofen selcctive electrodes. The Glycyrrhelinic Acid electrode exhibits Nernstian response with a slope 45mV/deeade(13℃) over the concentrations 10^(-6)mol/L～10^(-2)mol/L in the pH ranges from 7.6 to 10. 6. The detection limit is down to 6. 3× 10(-7)mol/L. Using direct potentiometric method to determine Subglycyrrhelinic acid the rate of recovery is from 98. 5to 101.8％. The Ibuprofen electrode exhibits Nernstian response with a slope of 58mV/decade(15℃)over the concentration 10^(-8)mol/L～10^(-2)mol/L in the pH ranges from 6.8 to 10.0. The detection limit is down to 8. 5×10^(-7)mol/L. Using direct potentiometric method to determine Ibuprofen the rate of recovery is from 97.59％ to 99.5％. The wide selectivity and good stability of the two electrodes show superior qualities.
出处
《内蒙古大学学报（自然科学版）》
CAS
CSCD
1993年第1期47-53,共7页
Journal of Inner Mongolia University：Natural Science Edition
关键词
二茂铁季铵盐
PVC膜
甘草次酸
布洛芬
ferrocene quaternary ammonium salt
ibuprofen
subglyeyrrhelinic acid
selective electrode
electroactive material
