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转录抑制因子ZHX1的研究进展 被引量:1

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摘要 锌指结构和同源框1(zinc-fingers and homeoboxes1。ZHX1)属于ZHX蛋白家族.ZHX蛋白家族还包括ZHX2、ZHX3.ZHX1开放阅读框编码873个氨基酸.其中包含2个锌指结构(C2-H2 zinc-fingers)和5个同源结构域。ZHX1可与其家族成员ZHX2和ZHX3结合形成异源二聚体。或自身结合形成同源二聚体.定位于细胞核中发挥调控转录作用。ZHX1蛋白在不同组织中广泛表达.但表达程度不尽相同.
作者 王振强 李琛
出处 《外科理论与实践》 2014年第3期270-272,共3页 Journal of Surgery Concepts & Practice
基金 上海市教委一般项目(13YZ025)
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