摘要
疟疾仍然是一个严重危害人类健康的公共卫生问题,尤其多见于发展中国家。随着认识的深入,间日疟也获得越来越多的重视。有效的药物治疗是控制疟疾甚至消除疟疾的基石,近年来已有越来越多的间日疟原虫氯喹抗性报道,间日疟原虫氯喹抗性已成为间日疟防治中一个备受关注的问题。本文就间日疟原虫氯喹抗性的分布现状、体内外检测方法和分子检测标志物研究进展进行初步总结。
Malaria remains a serious public health problem,especially in developing countries. With the deepening of the un-derstanding of vivax malaria,Plasmodium vivax is also attracting more and more attention. An effective drug treatment is the foun-dation of controlling or even eliminating malaria. In recent years,more and more reports of chloroquine-resistance Plasmodium vivax have been reported. Plasmodium vivax chloroquine resistance has been a focus problem in vivax malaria prevention and treat-ment. In this paper,the research progress on distribution situation,detection methods and molecular markers of Plasmodium vivax chloroquine resistance is summarized.
出处
《中国血吸虫病防治杂志》
CAS
CSCD
2014年第3期326-331,344,共7页
Chinese Journal of Schistosomiasis Control
基金
美国NIH研究项目(U19AI089672)
教育部科学技术研究重点项目(211079)
安徽省自然科学基金(1308085MH160)
蚌埠医学院研究生科研创新计划项目(Byycxz302)
关键词
间日疟原虫
氯喹
抗性
分子标记物
Plasmodium vivax
Chloroquine
Resistance
Molecular mark
