摘要
目的探讨癫痫持续状态(status epilepticus,SE)时血清心肌肌钙蛋白I(cardiac troponin I,cTnI)、肌酸激酶同工酶-MB(creatine kinase-MB,CK-MB)对患儿心肌损伤的诊断价值。方法测定60例SE患儿癫痫持续发作前和发作后6 h血清CK-MB和cTnI的水平,并与60例对照组患儿进行比较。结果病例组患儿癫痫持续发作后6 h血清CK-MB和cTnI均显著高于发作前和对照组,差异均有统计学意义(P均<0.05)。病例组患儿血清CK-MB和cTnI的阳性率分别为36.7%和26.7%,均显著高于对照组,差异均有统计学意义(P均<0.05)。结论 SE可引起患者心肌损伤。临床上在治疗SE时应动态监测CK-MB和cTnI水平,重视可能存在的心肌损伤。
Objective To evaluate the diagnosis value of the serum cardiac troponin I （cTnI） and creatine kinase-MB （CK-MB） in the diagnosis of myocardial injury in children with status epilepticus （SE）. Methods 60 children with SE （patient group） and 60 children without SE （control group） were selected. The levels of CK-MB and cTnI in two groups were detected. All data were analyzed statistically. Results Levels of serum CK-MB and cTnI in patient group after seizure 6 h were significantly higher than in patient group before seizure and control group, and the differences all had statistical significance （Pall〈 0.05）. The positive rates of serum CK-MB （36.7%） and cTnI （26.7%） in patient group were all higher than in control group. The differences all had statistical significance （Pall〈 0.05）. Conclusion Status epilepticus can cause myocardial injury. The levels of serum CK-MB and cTnI in patients with SE should dynamic monitoring in clinic, and should pay attention to myocardial injury.
出处
《实用检验医师杂志》
2014年第1期38-40,共3页
Chinese Journal of Clinical Pathologist
