摘要
急性肾损伤(AKI)是一种发生率和病死率较高的临床综合征。为提高对AKI的认识,有学者提出肾脏病发作的概念,其后透析质量指导组(ADQI)发布了2013广义AKI分类和诊断建议。ADQI广义标准将AKl分为单纯尿肾小管损伤标志物阳性、血清肌酐未升高和功能损伤标志物阳性(血清肌酐急性升高或尿量快速减少)两类。肾脏病发作概念及广义AKI诊断标准的提出将进一步推进AKI的早期诊断、预防和治疗决策。
Acute kidney injury(AKI)is a clinical syndrome associated with increased morbidity andmortality,and early recognition is critical.In an attempt to engage laypeople and non-experts,the term kidneyattack has been introduced to refer to acute kidney injury(AKI),and AKI with functional loss and tubulardamage can be diagnosed both with functional criteria(CRIAKI,creatinine increase AKI)and damagecriteria(NCRIAKI,non-creatinine increase AKI)according to the most recent ADQI consensus.Thiscomprehensive definition of Acute Kidney Syndromes may be a major advancement in terms of early referral,prevention of progression and therapeutic strategies for AKI.
作者
徐国宾
王国洪
刘德洪
王宏志
Xu Guobin;Wang Guohong;Liu Dehong;Wang Hongzhi(Key Laboratory of Carcinogenesis and Translational Research(Ministry of Education),Department of Clinical Laboratory,Peking University Cancer Hospital&Institute,Beijing 100142,China;不详)
出处
《中华检验医学杂志》
CAS
CSCD
北大核心
2014年第6期404-405,共2页
Chinese Journal of Laboratory Medicine
关键词
急性肾损伤
诊断
生物学标记
Acute kidney injury
Diagnosis
Biological markers
