摘要
目的了解中国山东省的癫病流行现况及其危险因素。方法以调查问卷为基础,运用国际统一癫诊断标准,采用多级分层随机整群抽样方法,逐户进行调查。结果调查人数251 492名,癫患者335例,癫患病率为1.33‰;男性患病率为1.35‰,女性患病率为1.31‰;城市患病率为1.20‰,农村患病率为1.39‰,均差异无统计学意义。癫发病率为18.69/10万。发作类型以全面性发作为主为60.90%;部分性发作为34.33%;发作不能分类为4.78%。首次发病平均年龄为(15.37±15.77)岁。特发性癫为60.90%,症状性癫为39.10%。大部分患者未进行正规治疗,治疗缺口为54.33%。结论山东省癫患病率、发病率处于全国较低水平,治疗缺口与国内文献报道一致。癫发作类型以全面性发作为主;癫发病以特发性癫为主,症状性癫病因中以脑炎为主。
Aim To investigate the epidemiological characteristics of epilepsy in Shandong province and the treatment condition.Methods The investigation which was based on the questionnaire was fulfilled by applying the international diagnostic standard epilepsy and using the way of stratified random cluster sampling and door-to-door survey.Results The epilepsy life-time prevalence was 1.33‰,of which the prevalence was 1.35‰ in male and 1.31‰ in female.No difference was found between the male and the female.The epilepsy prevalence was 1.39‰ in rural areas and 1.20‰ in urban areas.No difference was found between rural areas and urban areas.The incidence of epilepsy was 18.69/100000 per year.Of all the seizure types,generalized seizure was 60.90% in total,partial seizure account was 34.33%,unclassifiable seizure account for 4.77%.The average age of first seizure occurrence was (15.37 ± 15.77) years old.Among those patients,60.90% was diagnosed as idiopathic epilepsy and 39.10% was symptomatic epilepsy.Most of the people have not got regular treatment,the treatment gap was 54%.Conclusion The prevalence and incidence of epilepsy in Shandong were lower than other areas in China.Epileptic seizure type was given priority to generalized seizure.Epilepsy was given priority to idiopathic epilepsy.The cause of symptomatic epilepsy was given priority to encephalitis.Epilepsy treatment gap was 54.33%.
出处
《中国临床神经科学》
2014年第3期307-312,324,共7页
Chinese Journal of Clinical Neurosciences
基金
山东省自然基金资助项目(编号:ZR2011HL008)
山东省卫生厅课题(编号:2011HD017)