摘要
目的:探讨临床药师在重症感染患者救治中的作用。方法:临床药师参与1例重型脑外伤后合并肺部和真菌性血流感染患者的联合治疗,对抗感染药物治疗方案的制订提出了具体意见,采取先用亚胺培南/西司他汀然后降阶梯使用哌拉西林/他唑巴坦抗细菌感染,采用氟康唑抗真菌的联合抗感染的治疗方案,治疗的同时加强对必要的血常规、肾功能、肝功能,凝血功能药学监护。结果:临床药师提供的合理治疗方案取得了良好的治疗效果,患者体温、血常规、肾功能恢复正常,神志意识恢复,治愈出院。结论:临床药师通过实施药学监护,协助医师优化治疗方案,减少不必要的抗生素换用,提高了治疗效果,减少了细菌耐药和药品不良反应的发生。
Objective： To investigate the role of clinical pharmacist in the treatment of patients with severe infections. Methods： The clinical pharmacists participated in the combination therapy for one case of severe traumatic brain injury with pulmonary infection and fungal bloodstream infection, and provided suggestions for the anti-infective drug treatment made by the doctors. As for antibacterial, imipenem/cystatins were used first, and then piperacillin/tazobactam were taken by de-escalation therapy. Fluconazole was chosen as the antifungal agent. Meanwhile, the pharmaceutical care for blood routine examination, kidney function, liver function and blood coagulation were strengthened. Results ： The clinical pharmacists provided a reasonable regimen, a promising therapeutic effect was achieved, and the patient recovered. Conclusion： Through the implementation of pharmaceutical care, ctinical pharmacists can assist physicians in optimizing treatment regimen, reducing unnecessary antibiotic use, improving treatment effect, reducing bacterial resistance and adverse drug reactions,
出处
《中国药师》
CAS
2014年第6期1019-1021,共3页
China Pharmacist
关键词
临床药师
混合感染
治疗方案
药学监护
Clinical pharmacist
Mixed infection
Treatment regimen
Pharmaceutical care
