摘要
目的系统评价中西医结合疗法预防原发性肝癌术后复发的效果。方法计算机检索The Cochrane Library、PubMed、EMbase、中国期刊全文数据库(CNKI)、中文科技期刊数据库(VIP)、万方数据库(Wanfang Data)等数据库,收集所有中西医结合预防原发性肝癌术后复发的随机对照试验(RCT),检索时限均从建库至2013年6月。由2名评价员严格按照纳入标准筛选文献、提取资料和评价质量后,采用RevMan5.2软件对数据进行Meta分析。结果纳入文献共5篇,总病例数367例。Meta分析显示,中西医结合组在1、2、3年复发率控制方面均优于对照组(单纯西医治疗组),差异均有统计学意义(P<0.05)。结论与单纯的西医治疗组比较,中西医结合疗法在预防原发性肝癌术后复发方面效果更显著。
Objective To systematically evaluate the effectiveness of integrative medicine （IM） for preventing postoperative recurrence of primary hepatic carcinomas （PHC）. Methods Such databases as The Cochrane Library, PubMed, EMbase, China National Knowledge Infrastructure （CNKI）, VIP Database, Wanfang Database were retrieved to collect randomized controlled trials （RCTs） on preventing postoperative recurrence of PHC by IM. The retrieval period started from database establishment to June 2013. Literature screening, data extraction, and quality evaluation were performed by two reviewers strictly according to inclusion criteria. Meta-analysis was conducted using RevMan 5.2 Software. Results A total of 5 RCTs involving 367 patient cases were included. Results of Meta-analysis showed that the IM group was superior to the Western medicine （VVM） group in the 1-, 2-, and 3-year recurrence rates （P 〈0. 05）. Conclusion In the prevention of postoperative recurrence of PHC, the effectiveness of IM was more significant, when compared with treatment of Western medicine.
出处
《中国中西医结合杂志》
CAS
CSCD
北大核心
2014年第6期671-675,共5页
Chinese Journal of Integrated Traditional and Western Medicine
基金
广西中医药科技重大专项资助课题资助项目(No.GZKZ-Z1103)
国家科技部国际合作专项资助课题资助项目(No.2011DFA32620)
关键词
原发性肝癌
术后复发
中西医结合
META分析
系统评价
primary hepatic carcinoma
postoperative recurrence
integrative medicine
Meta analysis
systematic review
