摘要
常温条件下合成配合物[Zn(Bpp)Cl2]n(其中Bpp为1,3-双(4-吡啶)丙烷),并运用Bruker smart 1000 CCD-X射线单晶衍射仪对其结构进行表征.通过紫外光谱法、荧光光谱法及凝胶电泳法对其与DNA的作用进行研究,结果表明:此配合物能以嵌插方式与DNA作用,同时具备切割DNA能力.
The novel complex[Zn（Bpp）Cl2]n（Bpp =1,3-di（4-pyridyl） propane） was synthesized at room temperature,and characterized by Bruker smart 1 000 CCD-X-ray single crystal diffraction.The interaction with DNA was investigated by UV and fluorescence spectrum,and gel electrophoresis assay.The results showed that complex interacted with DNA and had DNA cleavage ability.
出处
《沈阳化工大学学报》
CAS
2014年第2期97-100,183,共5页
Journal of Shenyang University of Chemical Technology
基金
国家自然科学基金项目(20971090
21171118)
辽宁省特聘教授资助计划
沈阳市重点实验室资助项目(F10-215-1-00)
