摘要
目的:观察重症急性胰腺炎(SAP)肠外营养(PN)联合肠内营养(EN)与肠外营养治疗中各项指标的变化,分析二者疗效。方法:36例SAP随机分为PN组和PN+EN组例各18例,并均予以急性胰腺炎常规基础治疗。PN+EN组在PN后1周左右或生命体征平稳、肠功能恢复(有肛门排气、排便,腹胀减轻,肠鸣音恢复)后进行EN治疗,14d后观察疗效及化验指标的变化。结果:营养支持治疗14d后,各组血清白蛋白(ALB)、白细胞(WBC)和C反应蛋白较营养支持前均显着升高(P<0.01),二组ALP、WPC;各组APACHEⅡ评分较治疗前显着降低(P<0.01),PN+EN组评分显着低于PN组(P<0.01)。结论:PN+EN治疗SAP能够降低重症急性胰腺炎并发症发生率,提高临床疗效,值得推广应用。
Objective：Observation of severe acute pancreatitis （SAP） and parenteral nutrition （PN） and enteral nutrition （EN） and the changes of parenteral nutrition in the treatment of two, curative effect.Methods：36 cases of SAP were randomly divided into PN group and PN＋EN group were 18 cases each, and were treated with routine treatment of acute pancreatitis. PN＋EN group recovered in 1 weeks after PN or stable vital signs, intestinal function （with anal exhaust, defecate, decreased abdominal distension, bowel sounds recovery） after EN treatment,14 d to observe the changes of curative effect and laboratory indexes.Results：Nutrition support after 14 d treatment, the serum albumin （ALB）, white blood cell （WBC） and C reactive protein than before nutritional support were significantly increased （P〈0.01）, two groups of ALP, WPC;APACHE II score were significantly lower than before treatment （P〈0.01）, PN＋EN group was significantly lower than that of PN group （P〈0.01）. Conclusion：PN＋EN treatment of SAP can reduce the incidence of complications of severe acute pancreatitis, improve the clinical efficacy,is worthy of popularization and application.
出处
《中国医药导刊》
2014年第5期749-749,752,共2页
Chinese Journal of Medicinal Guide
关键词
重症急性胰腺炎
肠外营养
肠内营养
Severe acute pancreatitis
Parenteral nutrition
Enteral nutrition
