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咪达唑仑复合丙泊酚对全麻高血压患者的影响 被引量:3

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摘要 目的:探讨全麻术中的咪达唑仑复合不同剂量丙泊酚对高血压患者应激反应和血流动力学的影响。方法:全麻下行择期上腹部手术并存高血压患者60例,根据丙泊酚维持用量随机分为3组,A组3 mg·kg-1·h-1,B组5 mg·kg-1·h-1,C组7mg·kg-1·h-1;记录麻醉诱导前(T1)、气管插管后5min(T2)、切皮后2 min(T3)、手术探查(T4)及清醒拔管后(T5)各时点的HR、BP、CSI、CORT。结果:T2、T3、T4时A组比B组、C组HR快(P<0.05),T2、T3、T4、T5时A组比B组、C组SBP、DBP数值高(P<0.05),T2、T3、T4时A组比B组、C组CSI数值高(P<0.05),B组、C组CORT值在T2时刻降低(P<0.05),T3、T4、T5时A组比B组、C组高(P<0.05)。结论:咪达唑仑复合丙泊酚以5 mg·kg-1·h-1泵入维持麻醉时,高血压全麻患者各指标变化相对比较平稳。
出处 《中国中西医结合外科杂志》 CAS 2014年第3期311-312,共2页 Chinese Journal of Surgery of Integrated Traditional and Western Medicine
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