血小板膜糖蛋白与凋亡相关联的研究进展
TheResearch Progress of Platelet Membrane Glycoprotein Associated with Apoptosis
摘要
细胞凋亡,又称为"程序性的细胞死亡(programmed cell death,PCD)",是指机体为维持内环境的稳定,由基因控制的细胞自主的有序的死亡。自1972年Kerr等[1]首次发现凋亡现象以来,凋亡一直是人们研究的热点,但研究方向主要集中在有核细胞,随后经过20多年的研究,才逐步涉及无核细胞,乃至无核的血小板[2]。血小板的主要功能是凝血和止血,修补破损的血管;血小板的寿命平均为7~14d,体外保存平均为3~5d。
出处
《血栓与止血学》
2014年第3期141-143,共3页
Chinese Journal of Thrombosis and Hemostasis
参考文献20
-
1KERR JFR,WYLLIE AH,CURRIE AR,et al. Apoptosis:a basic bio- logical phenomenon with wide-ranging implications in tissue kinetics [ J]. British journal of cancer, 1972,26 (4) :239.
-
2VANAGS DM,ORRENIUS S, AGUILAR- SANTELISES M, et al. Al- terations in Bcl-2/Bax protein levels in platelets form part of an iono- mycin-induced process that resembles apoptosis [ J ]. British Journal of Haematology, 1997,99 (4) : 824 - 831.
-
3PIGUET PF, VESIN C. Modulation of platelet caspases and life-span by anti*platelet antibodies in mice [J]. European Journal of Haema- tology,2002,68 ( 5 ) :253-261.
-
4LI S,WANG Z,LIAO Y,et al. The glycoprotein Ibct-von Willebrand factor interaction induces platelet apoptosis [ J]. Journal of Thrombo- sis and Haemostasis,2010,8 ( 2 ) :341 - 350.
-
5LEYTIN V, ALLEN D J, MYKHAYLOV S, et al. Thrombin- triggered platelet apoptosis [J]. Journal of Thrombosis and Haemostasis,2006, 4(12) :2656-2663.
-
6LIN K H,CHANG HC,LU WJ,et al. Comparison of the relative ac- tivities of inducing platelet apoptosis stimulated by various platelet-ac-tivating agents[J]. Platelets,2009,20(8) :575-581.
-
7LEYTIN V, FREEDMAN J. Platelet apoptosis in stored platelet con- centrates and other models [ J ]. Transfusion and apheresis science, 2003,28(3) :285-295.
-
8VAN DER WAL DE, DU VX, LO KS, et al. Platelet apoptosis by cold-induced glycoprotein Ibct clustering [ J ]. Journal of Thrombosis and Haemostasis ,2010,8 ( 11 ) :2554-2562.
-
9LEYTIN V, ALLEN DJ, MYKHAYLOV S, et al. Pathologic high shear stress induces apoptosis events in human platelets [ J]. Biochemical and Biophysical Research Communications,2004,320(2) :303-310.
-
10DIANNE E, VAN DER WAL DE, Zhu G, et al. Desialylation : A novel platelet clearance mechanism and a potential new therapeutic target in anti-GP I b antibody mediated thrombocytopenia [ J ]. Blood (ASH Annum Meeting Abstracts) ,2012,120 : Abstract 265.
-
1张朝霞.沙眼衣原体在无核细胞中的生长[J].地方病译丛,1991,12(5):58-59.
-
2李欣,贾湘曼.睾丸生殖细胞凋亡及其调控因素研究进展[J].解剖学杂志,2003,26(5):501-504.
-
3朱启星,沈彤.细胞凋亡检测的研究进展[J].安徽医科大学学报,2002,37(6):411-414. 被引量:7
-
4李彦清.细胞凋亡的研究进展[J].实验动物科学与管理,2002,19(1):36-39. 被引量:2
-
5邓祖国,张勋.细胞凋亡的研究进展[J].黔南民族医专学报,1997,0(2):1-3.
-
6朱方,甄彦君,刘芳,周晓红.平滑肌细胞凋亡相关蛋白表达与中药的作用研究进展[J].河北中医药学报,2003,18(1):42-45.
-
7张向阳.细胞凋亡检测方法[J].济宁医学院学报,2008,31(3):258-260. 被引量:1
-
8李玲.细胞凋亡的分子机制及其调控因子[J].国外医学(免疫学分册),2002,25(6):317-320. 被引量:19
-
9朱书强,晏浩,徐建军.心肌细胞Fas/Fas_L系统与程序性细胞死亡相关研究进展[J].广东医学,2011,32(7):938-941. 被引量:5
-
10吕伟标,吕小迅.氢化可的松诱导大白鼠脾脏细胞的凋亡[J].中国煤炭工业医学杂志,2001,4(3):232-232. 被引量:1