摘要
目的:探讨中医药序贯治疗模式和巩固治疗模式对胃癌患者总生存和中位生存期的影响。方法:选取2007年1月至2010年7月于我院接受诊断和治疗的胃癌患者56例,按随机数字表法分为中医药序贯治疗组及中医药巩固治疗组,每组28例。通过观察患者总生存和中位生存期比较2组治疗效果。结果:中医药序贯治疗组患者总生存期显著高于中医药巩固治疗组(34月/21月,P<0.05),中医药序贯治疗组患者中位生存期显著高于中医药巩固治疗组(17.3月/8.2月,P<0.05),中医药序贯治疗组患者1年、2年和3年总生存率显著长于中医药巩固治疗组(1年67.9%/57.1%,2年28.6%/17.9%,3年17.9%/10.7%,P<0.05)。结论:中医药序贯治疗模式和中医药巩固治疗模式能够延长胃癌患者的总生存和中位生存期,且中医药序贯治疗模式效果更佳,值得临床推广应用。
Objective： To compare the overall survival and median survival time of gastric cancer patients after receiving traditional chinese medicine sequential therapy and consolidation therapy. Methods： 56 patients of gastric cancer were included,who received diagnosis and treatment in our hospital during the period of January 2007 to July 2010. They were randomly assigned into sequential therapy（ ST） group and consolidation therapy（ CT） group. Each group has 28cases. The overall survival and median survival time were compared between the two groups. Results： The overall survival time of ST group was significantly higher than CT group（ ST： 34 months /CT： 21 months,P〈0. 05）. The median survival time of ST group was significantly higher than CT group（ ST： 17. 3 months /CT： 8. 2 months,P〈0. 05）. The rate of survival of ST group during 1 year,2 years and 3 years were 67. 9%,28. 6% and 17. 9%,while 57. 1%,17. 9% and10. 7% of the CT group（ P〈0. 05）. Conclusion： Both traditional chinese medicine sequential therapy mode and consolidation therapy mode can efficiently prolong the overall survival and median survival time of gastric cancer; and the efficiency of the traditional chinese medicine sequential therapy mode was much better than the traditional chinese medicine consolidation therapy mode. It is worth to promote in clinic.
出处
《中国中医基础医学杂志》
CAS
CSCD
北大核心
2014年第6期801-803,共3页
JOURNAL OF BASIC CHINESE MEDICINE
关键词
中医药序贯治疗
中医药巩固治疗
胃癌
总生存期
中位生存期
Traditional Chinese Medicine Sequential Therapy Mode
Traditional Chinese Medicine Consolidation Therapy Mode
gastric cancer
overall Survival
median Survival Time.
