摘要
目的探讨腹膜透析相关性腹膜炎的致病菌及其耐药性。方法腹膜透析相关性腹膜炎患者84例,对腹膜炎致病菌的耐药性进行检测,随访治疗结果。结果 84例患者发生腹膜透析相关性腹膜炎93例次,细菌培养阳性65例次(69.9%),其中革兰阳性菌40例次,革兰阴性杆菌19例次,真菌6例次。对革兰阳性菌耐药率较高的是青霉素G、苯唑西林和头孢唑啉;革兰阴性菌中耐药率较高的是氨苄西林、头孢他啶和头孢呋辛钠。真菌感染患者预后差。结论腹膜透析相关性腹膜炎的致病菌谱不断变化,应严格把握抗生素的适应证,减少耐药菌株的产生。
Objective To investigate the pathogens and drug resistance of peritoneal dialysisrelated peritonitis. Methods Eighty-four patients occurred peritoneal dialysis-related peritonitis for 93 times. The bacterial culture and drug sensitivity test were performed and therapeutic results were followed up. Results A total of 65 （69.9%） cases was bacterial culture positive, of which Gram- positive bacteria was found in 40 times, Gram-negative bacilli in 19 times and fungi in 6 times. Resistant drugs against Gram-positive bacteria with higher rate were penicillin G, oxacillin, and cefazolin. Resistant drugs against Gram-negative bacteria with a higher rate were ampicillin, ceftazidime and cefuroxime sodium. The patients with fungal infections had poorer prognosis. Conclusion Spectrum of pathogen in peritoneal dialysis-related peritonitis is changeable. To reduce the strans with drug resistance, the indications for antibiotics use should be strictly grasped.
出处
《江苏医药》
CAS
北大核心
2014年第11期1309-1311,共3页
Jiangsu Medical Journal
关键词
腹膜透析
腹膜炎
病原菌
耐药
Peritoneal dialysis
Peritonitis ~ Pathogens ~ Drug resistance
