摘要
目的 比较非炎性前部缺血性视神经病变（NAION）和特发性视神经炎（ION）的眼灌注压与眼部血流动力学,分析其与固视性质之间的关系.方法 回顾性病例研究.收集2011年3月至2013年5月间在中国医科大学附属第四医院眼科诊治的NAION和ION患者的病例资料,记录患者的发病年龄、性别组成、全身疾病;按固视性质分为中心视力和中心外视力,比较眼灌注压和眼部血流动力学的差异,分析造成这些差异的原因.结果 NAION患者21例21只眼（中心视力者14只眼、中心外视力者7只眼）,ION患者21例21只眼（中心视力者8只眼、中心外视力者13只眼）.中心视力眼中,睫状后动脉和视网膜中央动脉的收缩期峰速在NAION组明显低于ION组,差异有统计学意义（t=12.49,P=0.00;t=14.25,P=0.00）;中心外视力眼中,坐位肱动脉的平均动脉压和眼灌注压NAION组明显高于ION组、睫状后动脉和视网膜中央动脉的收缩期峰速NAION组明显低于ION组,差异有统计学意义（t =6.41,P=0.02;t=5.66,P=0.03;t=8.47,P=0.01;t=11.32,P=0.00）.不按固视性质分类,仍然将视力都按中心视力统计,睫状后动脉和视网膜中央动脉的收缩期峰速NAION组明显低于ION组,差异均有统计学意义（t=5.81,P=0.02;t=9.20,P=0.00）.结论 NAION和ION患眼的固视性质有中心视力和中心外视力之分,比较眼灌注压、眼部血流动力学指标也要分别统计.
Objective To compare the Ocular perfusion pressure （OPP） and ocular hemodynamics of patients with non-arteritic anterior ischemic optic neuropathy （NAION） and idiopathic optic neuritis （ION）,and analyze their relationship with fixation features.Methods It was a retrospective case study.Data were collected in patients with NAION and ION who were treated in Department of Ophthalmology,the Fourth Affiliated Hospital,China Medical University from March 2011 to May 2013.OPP and ocular hemodynamics were analyzed,as well as the ages,gender,and systemic diseases after these patients were divided as the central fixation group and the extra-central fixation one on the basis of ocular fixation features.The reason making the differences were thought over.Results There were 21 NAION cases （21 eyes,14 for central fixation and 7 for extra-central fixation） and 21 ION ones （21 eyes,8 for central fixation and 13 for extra-central fixation）.The peak systolic velocity （PSV） of posterior ciliary artery （PCA） and central retinal artery （CRA） were significantly decreased in the NAION group comparing with the ION group in central fixation eyes （t =12.49,P =0.00; t =14.25,P =0.00）.In the extra-central fixation eyes,the sitting mean artery pressure （MAP） of brachial artery and OPP were significantly increased in the NAION group,and the PSV of PCA and CRA were significantly decreased in the NAION group （t =6.41,P =0.02; t =5.66,P =0.03; t =8.47,P =0.01; t =11.32,P =0.00）.However,the PSV of PCA and CRA were significantly decreased in the NAION group when the fixation features were excluded from the classification criteria and all kinds of vision was regarded totally as central fixation vision （t =5.81,P =0.02; t =9.20,P =0.00）.Conclusions The fixation features of NAION and ION eyes can be classified as central fixation and extra-central fixation.The comparisons of OPP and ocular hemodynamics should be classified according to the fixation features.
出处
《中国实用眼科杂志》
CSCD
北大核心
2014年第6期725-728,共4页
Chinese Journal of Practical Ophthalmology
关键词
非动脉炎性前段缺血性视神经病变
特发性视神经炎
眼灌注压
眼部血流动力学
Non-arteritic anterior ischemic optic neuropathy （NAION）
Idiopathic optic neuritis （ION）
Ocular perfusion pressure （OPP）
Ocular hemodynamics
