摘要
目的:回顾性分析硬化性乳腺病的临床病理以及影像学特点。方法:选取2011-01-01-2012-12-30湖南省湘潭市第一人民医院(871例)及湘潭市中心医院乳腺外科(632例)接受手术治疗乳腺疾病患者1 503例,对有硬化性乳腺病患者的流行病学资料、临床病理资料、影像学资料以及随访资料等信息进行整理分析。结果:1 503例乳腺疾病患者中,39例(2.6%)患者患有或伴有硬化性乳腺病,X射线钼靶与超声检测对于硬化性乳腺病伴随乳腺癌的检测准确性分别为45.7%和60.0%,两者联合诊断的准确性为34.3%。空心针穿刺与术中冷冻判断硬化性乳腺病相关乳腺疾病的良恶性的低估率分别为42.9%和60.0%。有6例(15.4%)硬化性乳腺病患者同时伴有乳腺癌。结论:硬化性乳腺病缺乏特异性的临床表现与影像学表现,多数硬化性乳腺病患者需要依靠术后详细的病理检测才能明确良恶性。患有硬化性乳腺病的患者同时伴有恶性病变的风险较高,病理诊断为硬化性乳腺病的患者需密切随访。
OBJECTIVE: To evaluate the elinicathological and imaging characteristics of sclerosing adenosis. METH- ODS: Clinicopathological and imaging data were collected from patients with sclerosing adenosis diagnosed between 1st Jan. 2011 and 30th Dec. 2012. RESULTS.. Among the 1 503 patients with breast diseases,a total of 39 patients (2.6%) were diagnosed as sclerosing adenosis related breast disorders. The accuracy of ultrasound and mammography for patients with sclerosing adenosis were 45.7 % and 60.0%. The underestimate rate for core needle biopsy and open biopsy in diagnosing sclerosing adenosis related disorders were 42.9 % and 60.0 %. About 15.4 % (n=6) of the patients with sclerosing adenosis were accompanied by breast cancer. CONCLUSIONS: Sclerosing adenosis lacks of specific clinical manifestations and. imaging findings. The diagnosis of the majority of patients with sclerosing adenosis may rely on the final histopathology. The risk of growing malignancy was relatively high for paitents with sclerosing adenosis and close follow-up is needed.
出处
《中华肿瘤防治杂志》
CAS
北大核心
2014年第12期945-947,共3页
Chinese Journal of Cancer Prevention and Treatment
关键词
乳腺肿瘤
硬化性乳腺病
超声
钼靶
breast neoplasms
sclerosing adenosis
ultrasound
mammography