摘要
目的:通过临床观察收集中医四诊信息,运用统计学分析法,探讨"气运失常"贯穿肺纤维化全病程这一理论认识。方法:将所收集的200例患者应用系统聚类分析方法,对中医临床四诊信息进行分层聚类指标变量分析,应用Mann-Whitney U检验分析与"气运失常"相关的临床症状在各期的分布表达。结果:聚类分析结果显示,200例IIP患者从整体层面可以分为肺泡炎期和纤维化期,且咳嗽、喘息、乏力三种症状在两期的分布表达无统计学意义,但症状程度在两期的表达有统计学意义(P<0.05)。结论:肺气虚证是肺纤维化的临床常见证候,"气运失常"贯穿IIP全病程。
Objective： Collecting the information of four diagnostic methods of TCM through clinical observation, applying sta- tistical analysis method, to explore the theory of disorder of Qi activity throuth the process of idiopathic interstitial pneumonia （IIP）. Methods： We collected 200 cases of patients and analyse the four diagnostic methods of TCM with hierarchical cluster analysis of indi- cator variables; We analysed the distribution of clinical symptoms associated with disorder of Qi activity in each period with Mann- Whitney U test. Results： The cluster analysis shows that 200 cases of IIP patients as a whole can be divided into alveolitis and fibrosis stage, and there is no difference in the expression of cough, wheezing and weak between the two stages, but the symptoms level has statistical significance （ P 〈 0. 05 ） . Conclusions ： The syndrome of Qi deficiency of lung is a common clinical syndrome of pulmonary fibrosis, and disorder of qi activity runs throuth the whole process of idiopathic interstitial pneumonia （IIP）
出处
《成都中医药大学学报》
2014年第2期69-71,共3页
Journal of Chengdu University of Traditional Chinese Medicine
基金
"泰山学者"建设工程专项经费资助(编号:ts20110819)
山东省2009-2010年度中医药科技发展计划(编号:2009-072)
