摘要
目前临床医生一直在关注乙肝肝硬化抗病毒治疗的疗程以及如何达到治疗目标、药物副反应如何认识等。该文重点论述了肝硬化诊断与分期,患者抗病毒治疗的重要性及治疗目标、疗程。5个核苷(酸)类似物的临床特点,强调了抗病毒治疗可以延缓肝病进展,但不能改变其终末期肝硬化最终结局的现实。同时提出乙型肝炎肝硬化患者及时抗病毒治疗是必须的,而抗肝纤维化治疗是必要的临床实践理念。
Researchers within China and worldwide have come to a consensus on antiviral treatment of iLiver cirrhosis with hepatitis B,which has been written in the domestic and foreign relevant guidelines. Clinicians have been paying attention to the antiviral treatment of liver cirrhosis, how to achieve the goal of treatment, and how to treat drug-induced side effects, etc. This paper mainly discusses the diagnosis and staging of liver cirrhosis, importance and goal of antiviral treatment, course of treatment, and clinical characteristics of five nucleoside analogues （acid） , emphasizes that antiviral treatment can only slow progression in liver disease, but cannot change the results of end end-stage liver cirrhosis. The author considers that timely antiviral treatment is essential and anti-fibrosis treatment is necessary for liver cirrhosis with hepatitis B patients in clinical practice. Meanwhile, compliance should be introduced at the same time to patients, because compliance education is the key to achieve treatment goals.
出处
《中国实用内科杂志》
CAS
CSCD
北大核心
2014年第6期568-571,共4页
Chinese Journal of Practical Internal Medicine
关键词
肝硬化
慢性乙型肝炎
核苷(酸)类似物
liver cirrhosis
chronic hepatitis B
antiviral treatment
nucleoside analogues
