摘要
目的建立了盐酸左氧氟沙星片微生物限度的检测方法,并对方法学进行验证。方法采用低速离心结合薄膜过滤手段建立盐酸左氧氟沙星片的微生物限度检测方法。结果细菌计数及控制菌用薄膜过滤法检查,霉菌及酵母菌计数用常规法检查。结论该方法准确、可靠,适用于左氧氟沙星片的微生物检查。
Objective To develop and validate a method for microbial limit detection of levofloxacin hydrochloride tablets.Methods Low-speed centrifugation and membrane filtration approaches were used for the development of microbial limit detection method for levofloxacin hydrochloride tablets.Results The bacteriad and the control of bacteria were determined by membrane filtration approach,molds and yeast were determined by routine approach. Conclusion The method is accurate,reliable,and suitable for detection of the microbial limit of levofloxacin hydrochloride tablets.
出处
《中国药物经济学》
2014年第5期16-17,共2页
China Journal of Pharmaceutical Economics
关键词
左氧氟沙星片
微生物限度
方法学
建立
验证
Levofloxacin tablets
Microbial limit detection
Method
Development
Validation
