摘要
长期服用氢氯噻嗪引起抗利尿激素不适当分泌综合征(SIADH)的病例临床比较少见,容易误诊或漏诊。该文报道1例因头晕、乏力就诊的老年女性,入院后结合实验室检查及排除其他引起低钠血症的病因后可基本明确诊断为SIADH。经停药、纠正水负荷过多及积极补钠后血钠恢复正常。该例提示,如果患者有长期服用氢氯噻嗪病史,且伴有低钠血症时,应考虑到SIADH的可能性。
Inappropriate secretion of antidiuretic hormone syndrome （SIADH）caused by long term administration of hydrochlorothiazide is a rare and easily misdiagnosed complication in clinical practice. This paper reports a case of elderly patient with dizziness and fatigue,who was diagnosed as SIADH after careful laboratory examination and differentiated diagnosis of other causes of hyponatremia. With hydrochlorothiazide withdrawal,water overload correction and sodium supplement,the blood sodium level returned to normal range. This case suggests that if a patient with hyponatremia has a history of long term hydrochlorothiazide usage,consideration should be given to the possibility of inappropriate secretion of antidiuretic hormone syndrome.
出处
《新医学》
2014年第5期345-347,共3页
Journal of New Medicine
关键词
抗利尿激素不适当分泌综合征
氢氯噻嗪
低钠血症
Syndrome of inappropriate antidiuretic hormone secretion
Hydrochlorothiazide
Hyponatremia
