摘要
制备出HLB值从 4.3～ 14之间的新城疫 (ND)油苗 10组 ,分别免疫 3月龄易感来航鸡 ,每隔 1～ 2周采血直至第 8周 ,进行HI抗体测定 ,HLB值为 7.0时ND油苗产生的抗体水平最高。HLB值为 7.0的油苗油相中乳化剂含量为 10 % ,油水比例为 4∶1时 ,其产生的HI抗体最高。试验结果表明油苗的HLB值、乳化剂含量、油相水相之间比例对油苗效果起关键性作用。
Preparations of inactivated Newcastle disease(ND) oilemulsion Vaccines with surfactant hydrophile_lipophile blance(HLB)values between 4.3 to 14 were evaluated for their efficacy.White leghorn chickens were vaccinated in 3 months and bled at 1_2 weeks intervals over 8 weeks.Based on HI response,an HLB Value of 7.0 induced the greatest stimulation of antibody titers.Ten per_cent surfactant in oil phase,oil:aqueous ratios of the vaccines with HLB values 7.0 induced maximum titers at this HLB.These results indicate that HLB values,the percentage of surfactant in oil phase,the oil:aqueous ratios of the vaccines may maximize the efficacy of vaccines.
出处
《中国预防兽医学报》
CAS
CSCD
北大核心
2001年第2期127-129,共3页
Chinese Journal of Preventive Veterinary Medicine
基金
广西科技攻关项目
广西畜牧局科技经费的资助
关键词
亲油亲水平衡值
新城疫油苗
鸡
疫苗
免疫力
Hydrophile_lipophile balance
Newcastle disease virus oil_emulsion vaccines
Effection
