摘要
目的探讨经内镜氩离子凝固术(APC)治疗隆起糜烂性胃炎(EGP)的价值及安全性。方法选取100例EGP患者分为观察组与对照组(各50例),观察组行APC治疗,合并幽门螺杆菌(H.pylori)感染者服用兰索拉唑、阿莫西林、克拉霉素治疗7 d,无H.pylori感染者口服兰索拉唑治疗,治疗8周后患者复查胃镜评价疗效。结果手术过程顺利,未发生灼伤、穿孔等严重并发症;观察组患者症状改善明显优于对照组(P<0.05),观察组症状治疗总有效率(98.00%)明显高于对照组(84.00%)(P<0.05),观察组患者内镜下观察病灶改善明显优于对照组(P<0.05),观察组内镜下治疗总有效率(100%)明显高于对照组(66.00%)(P<0.05),观察组隆起糜烂病灶减少率(91.14%)高于对照组(42.27%)(P<0.05),H.pylori阳性患者治疗转阴率为81.58%,对照组为74.29%,差异无统计学意义(P>0.05)。结论经内镜APC治疗疗效确切,明显高于单纯药物治疗,手术安全性高,值得临床推广。
Objective To investigate the value and safety of endoscopic argon plasma coagulation （APC） in treatment of erosive gastritis protuberans.Methods One hundred cases of erosive gastritis protuberans were divided into observation group and control group,50 patients in the observation group received endoscopic APC treatment,patients who infected Helicobacter pylori （H.pylori） received lansoprazole,amoxicillinxillin,carat enzyme for 7 d,patients who didn＇ t infect H.pylori took orally lansoprazol.Curative effect was evaluated by endoscopy after 8 weeks treatment.Results The operation went smoothly,no serious complications such as burn and perforation happened.Symptom improvement in observation group was better than that in control group （P ＜ 0.05）,total effective rate was significantly higher in observation group （98.00％） than that in control group （84.00％,P ＜ 0.05）.Leaions improvement under was better in observation group than that in control group （P ＜ 0.05）.Total effective rate under endoscopy was significantly higher in observation group than that in control group （100％ vs 66.00％,P ＜ 0.05）.Erosive lesions reducing rate was higher in the observation group than that in control group （91.14％ vs 42.27％,P ＜ 0.05）.There was no significant difference in negative conversion rate of H.pylori positive patients between observation group and control group （81.58％ vs 74.29％,P ＞ 0.05）.Conclusion Endoscopic APC treatment of erosive gastritis protuberans is effect and safe.
出处
《胃肠病学和肝病学杂志》
CAS
2014年第5期520-522,共3页
Chinese Journal of Gastroenterology and Hepatology
关键词
隆起糜烂性胃炎
胃镜
氩离子凝固术
Erosive gastritis protuberans
Gastroscopy
Argon plasma coagulation
