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快速康复外科理念应用于胃癌患者围手术期的前瞻性随机对照研究 被引量:66

Promotion of postoperative recovery with fast track surgery for gastric cancer patients ;undergoing gastrectomy:a prospective randomized controlled study
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摘要 目的:探讨快速康复外科(FTS)理念应用于胃癌患者围手术期管理对促进患者术后康复的安全性和有效性。方法前瞻性入组2013年1-11月间河南科技大学第一附属医院胃肠肿瘤外科收治的71例胃癌患者,按随机数字表法随机分为干预组和对照组,干预组按照FTS方案管理,对照组按照传统方式管理,比较两组术后恢复情况及应激程度。结果干预组较对照组术后通气时间提前[(67.8±19.7) h比(90.0±20.6) h, P<0.01]、术后住院时间缩短[(13.5±3.0) d比(17.8±7.3) d, P=0.01]、住院费用降低[(2.38±0.37)万元比(2.78±0.61)万元, P<0.05],且术后疼痛评分、白细胞及C反应蛋白等应激指标降低(均P<0.01),肠梗阻、感染、吻合口瘘等术后并发症发生率并未增高(均P>0.05)。结论 FTS应用于胃癌患者围手术期管理可减轻术后应激,促进患者术后康复。 Objective To study the safety and feasibility of fast track surgery (FTS) in the promotion of postoperative recovery for gastric cancer patients undergoing gastrectomy. Methods From January to December in 2013, 71 gastric cancer patients were prospectively enrolled and randomized into the FTS group and the control group. Patient in the FTS group received FTS management and those in the control group received routine management. The postoperative recovery and stress were compared between the two groups. Results FTS was associated with shorter time to bowel function return[(67.8±19.7) h vs. (90.0±20.6) h, P〈0.01], shorter hospital stay [(13.5±3.0) d vs. (17.8±7.3) d, P=0.01], lower hospital cost [(23.8±3.7) thousand Yuan vs. (27.8±6.1) thousand Yuan, P〈0.05], and less stress response(lower pain score, WBC count, C-reactive protein, all P〈0.01). The postoperative complications including ileus, infection, anastomotic leakage were similar (all P>0.05). Conclusion Fast track surgery decreases postoperative stress response and promotes recovery.
出处 《中华胃肠外科杂志》 CAS CSCD 2014年第5期489-491,共3页 Chinese Journal of Gastrointestinal Surgery
关键词 胃肿瘤 快速康复外科 应激反应 术后并发症 Stomach neoplasms Fast track surgery Stress Postoperative complications
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  • 1郑海波,傅俊惠,吴智勇,李学明,章克毅,郑春鹏,黄建豪.食管癌术后早期肠内营养预防肺部感染的临床研究[J].中华医院感染学杂志,2005,15(12):1361-1363. 被引量:14
  • 2江志伟,李宁,黎介寿.快速康复外科的概念及临床意义[J].中国实用外科杂志,2007,27(2):131-133. 被引量:1380
  • 3黎介寿.对Fast-track Surgery(快通道外科)内涵的认识[J].中华医学杂志,2007,87(8):515-517. 被引量:373
  • 4黎介寿.营养与加速康复外科[J].肠外与肠内营养,2007,14(2):65-67. 被引量:211
  • 5Suttner S,Lang K,Piper SN,et al.Continuous intra-and postoperative thoracic epidural analgesia attenuates brain natriuretic peptide release after major abdominal surgery[J].Anesth Analg,2005,101(3):896.
  • 6Freise H,Meissner A,Lauer S,et al.Thoracic epidural analgesia with low concentration of bupivacaine induces thoracic and lumbar sympathetic block:a randomized,double-blind clinical trial[J].Anesthesiology,2008,109(6):1107.
  • 7Mayer J,Boldt J,Schellhaass A,et al.Bispectral index-guided general anesthesia in combination with thoracic epidural analgesia reduces recovery time in fast-track colon surgery[J].Anesth Analg,2007,104(5):1145.
  • 8Taqi A,Hong X,Mistraletti G,et al.Thoracic epidural analgesia facilitates the restoration of bowel function and dietary intake in patients undergoing laparoscopic colon resection using a traditional,nonaccelerated,perioperative care program[J].Surg Endosc,2007,21(2):247.
  • 9Kuo CP,Jao SW,Chen KM,et al.Comparison of the effects of thoracic epidural analgesia and i.v.infusion with lidocaine on cytokine response,postoperative pain and bowel function in patients undergoing colonic surgery[J].Br J Anaesth,2006,97(5):640.
  • 10Kehlet H, Wilmore DW. Multimodal strategies to improve surgical outcome. Am J Surg, 2002,183(6) :630-641.

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