摘要
【目的】观察负压封闭引流技术（ VSD ）在大面积皮肤缺损植皮修复术围手术期的应用效果。【方法】45例大面积皮肤缺损的患者植皮前先采用VSD治疗7～14 d培养肉芽，植皮术后继续予以VSD治疗（VSD组）7～10 d。42例皮肤缺损患者予以传统换药、单纯皮片移植术并采用传统打包加压治疗（传统组）。比较两组的植皮成活率及住院时间。【结果】VSD组植皮成功率88．89％，感染率2．22％，住院时间（30．4±3．8）d；传统组植皮成功率66．67％，感染率19．05％，住院时间（52．8±7．2）d。两组植皮成功率比较，差异有统计学意义（χ2＝6．28，P ＜0．05）；两组感染率比较，差异有统计学意义（χ2＝4．94，P ＜0．05）；住院时间比较，差异有统计学意义（ t ＝2．45，P ＜0．05）。【结论】大面积皮肤缺损创面的修复，植皮术围术期采用 VSD治疗，可促进创面的愈合，提高植皮成功率，降低感染率，缩短治疗时间。
[Objective] To observe the application effect of vacuum sealing drainage （VSD） in the dermato-plasty for large area of cutaneous defect during the operation .[Methods] Totally 45 patients with large area of cutaneous defect received VSD to cultivate the granulation before dermatoplasty for 7~14d ,and then continu-ously received VSD for 7~10d after dermatoplasty （VSD group） .Another 42 patients with cutaneous defect were given traditional dressing change ,simple skin grafting and conventional package and compression （tradi-tional group） . The survival rate of the grafted skin and hospitalization time were compared between two groups .[Results]In VSD group ,the successful rate of dermatoplasty was 88 .89% ,and the infection rate was 2 .22% ,and the hospitalization time was （30 .4 ± 3 .8）d .In traditional group ,the successful rate of dermato-plasty was 66 .67% ,and the infection rate was 19 .05% ,and the hospitalization time was （52 .8 ± 7 .2）d . There was significant difference in the successful rate of dermatoplasty between two groups （χ2 =4 .94 ,P 〈0 .05） .There was also significant difference in hospitalization time between two groups （ t=2 .45 ,P〈0 .05） .[Conclusion] VSD applied in the dermatoplasty for repairing large area of skin defect wound during the opera-tion can promote the wound healing ,increase the successful rate ,reduce the infection rate and shorten the treatment duration .
出处
《医学临床研究》
CAS
2014年第4期682-684,687,共4页
Journal of Clinical Research
