摘要
目的应用二维斑点追踪成像技术评价正常成人颈动脉环向应变,并探讨影响颈动脉环向应变的相关因素。方法 129例健康正常成人根据年龄分为青年组(40例)、中年组(54例)及老年组(35例)。应用超声射频信号血管内中膜定量分析(QIMT)技术和动脉僵硬度定量分析(QAS)技术分别测量左侧颈动脉内中膜厚度(IMT)和僵硬度参数(β),应用二维应变软件分析左侧颈动脉环向应变峰值(GPCS),比较各颈动脉参数的差异,并分析GPCS的影响因素。结果①三组间IMT、β及GPCS比较差异均有统计学意义(P﹤0.05),老年组IMT和β高于青年组和中年组,GPCS低于青年组和中年组;②多元线性回归分析表明年龄、舒张压与GPCS呈负相关(r=-0.682、-0.210,P﹤0.05),脉压差与GPCS呈正相关(r=0.164,P﹤0.05)。结论正常成人颈动脉IMT、β及GPCS随年龄增加而变化;年龄、舒张压及脉压差是GPCS的影响因素。
Objective To evaluate carotid arterial circumferential strain（CACS） in health subjects by two-dimensional speckle tracking imaging（ STI ）.Methods A total of 129 health subjects were enrolled and were divided into 3 groups according to age, including youth group （ n =40 ）, middle-aged group （ n =54 ） and old age group （ n =35 ）.The intima media thickness （IMT） and stiffness parameter [5 of left common carotid artery in all subjects were measured by QIMT and QAS techonolgies.The peak of left CACS（ GPCS ） was analyzed by STI technology.The CACS parameters were compared among three groups.Multiple linear regression analysis was performed to identify determinants of GPCS. Results ①The IMT and β were higher, while the GPCS was lower in old age group compared with those in youth and middle-aged group with statistically significant differences （P 〈 0.05 ）. ②The results of multiple linear regression analysis showed age and diastolic blood pressure were negatively correlated with GPCS （r=-0.682,-0.210,P 〈 0.05）,while pulse pressure was positively with GPCS （r=0.164,P 〈 0.05）. Conclusion In normal population, the IMT, β and GPCS change with increasing age.Age, diastolic pressure and pulse pressure are the most important factors of GPCS.
出处
《临床超声医学杂志》
2014年第4期228-230,共3页
Journal of Clinical Ultrasound in Medicine
关键词
斑点追踪成像
二维
颈动脉
动脉弹性
环向应变
Speckle tracking imaging, two-dimensional
Carotid artery
Arterial elasticity
Circumferential strain
