摘要
急性肾损伤(acute kidney injury,AKI)是肝硬化最严重的并发症之一。肝硬化背景下的肾损伤在临床上可分为AKI、慢性肾病和慢加急性肾病。Ⅰ型肝肾综合征(hepatorenal syndrome,HRS)是一种特殊类型的AKI,Ⅱ型HRS属于慢性肾功能衰竭,有学者还提出所谓具有肾脏结构性病变的Ⅲ型HRS。本文介绍了近年关于肝硬化AKI的诊断、分类、进展规律、预后及防治等方面的新进展。
Acute kidney injury (AKI) is one of the most severe complications in patients with liver cirrhosis. The kidney in-jury in the background of liver cirrhosis can be classified into AKI, chronic kidney disease and acute-on-chronic kidney disease. Type 1 hepatorenal syndrome (HRS) is a special kind of AKI, type 2 HRS belongs to chronic kidney failure, and the recently pro-posed type 3 HRS is the type with kidney structural injury. This review focuses on the recent research progress of diagnosis, classifi-cation, progression, prognosis, prevention and treatment of AKI in patients with liver cirrhosis.
出处
《传染病信息》
2014年第2期69-73,共5页
Infectious Disease Information
基金
南京军区"十一五"医药科技项目(09Z011
06MA63)
关键词
肝硬化
急性肾损伤
肝肾综合征
liver cirrhosis
acute kidney injury
hepatorenal syndrome