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肥大细胞在抗感染免疫作用中的研究进展

Research development of mast cells in anti-infection immune function
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摘要 肥大细胞是广泛分布于全身组织中重要的固有免疫细胞。近年来研究发现,肥大细胞除参与IgE介导的超敏反应外,在机体抗感染免疫中也发挥重要的作用。该细胞不仅参与固有免疫应答,直接识别、吞噬、杀灭病原菌,还参与加工、处理、提呈抗原,启动和调节适应性免疫应答。 Mast cells are innate immune cells which widely distribute in the body＇s connective tissue. In recent years, its reported that mast cells not only play an important role in allergic reactions but also play an important role in the body against pathogens. Mast cells not only have the function to identify, phagocytose and kill pathogenic microorganisms, but also through release of cytokines participate in the innate immune response, and can present antigen, regulation of adaptive immune response.
作者 王晓曼 王静茹 王梦 曹志然
机构地区 河北大学基础医学院
出处 《医学研究与教育》 CAS 2014年第2期87-92,共6页 Medical Research and Education
基金 河北省自然科学基金资助(C2011204008) 河北大学医学学科专项资金建设项目(2012A2005) 2013年地方高校国家级大学生创新创业训练计划项目(201310075016)
关键词 肥大细胞 细菌感染 病毒感染 免疫应答 Mast cells bacterial infection viral infection immune response
分类号 R392 [医药卫生—免疫学]
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参考文献29

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二级参考文献18

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医学研究与教育
2014年 第2期

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