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肾积水后相关信号分子的研究现状

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摘要 肾积水（Hydronephrosis）是由于尿路梗阻而引起的肾盂肾盏扩张并伴有肾组织的萎缩.目前研究已经明确许多蛋白信号分子在肾积水后肾功能损伤的发生发展中发挥了重要的调节作用,并影响着肾功能的损害及其纤维化的发生及发展,但在基因水平尤其是MicroRNAs调控的信号通路在肾积水后肾功能的改变上还没有明确的研究证实,研究这些信号分子及MicroRNAs将为尿路梗阻后肾积水引起的肾功能损害以及后期解除梗阻后肾功能的恢复提供新的治疗思路.
作者 刘亚明 崔苏萍
机构地区 南昌大学第一附属医院 南昌大学第一附属医院泌尿外科
出处 《国际泌尿系统杂志》 2014年第3期440-445,共6页 International Journal of Urology and Nephrology
关键词 肾盂积水 纤维化 微RNAS
分类号 R692.2 [医药卫生—泌尿科学]
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参考文献38

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国际泌尿系统杂志
2014年 第3期

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